long-chain-aldehyde dehydrogenase

RefSeq NM_000382 (human)

Also Known As:

ALDH10 protein, human; ALDH3A2 protein, human; aldehyde dehydrogenase 3 family, member A2 protein, human; fatty aldehyde dehydrogenase; fatty-aldehyde dehydrogenase; long chain fatty aldehyde dehydrogenase

Networked: 71 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxidoreductases Acting on Aldehyde or Oxo Group Donors
      - Aldehyde Oxidoreductases: 1
        long-chain-aldehyde dehydrogenase: 71

Experts

1.	Rizzo, William B: 14 articles (03/2022 - 08/2004)
2.	Wanders, Ronald J A: 7 articles (07/2012 - 05/2004)
3.	Keller, Markus A: 5 articles (01/2021 - 06/2010)
4.	Carney, Gael: 5 articles (11/2011 - 08/2004)
5.	Rotteveel, J J: 4 articles (07/2001 - 02/2000)
6.	Willemsen, M A: 4 articles (07/2001 - 02/2000)
7.	Kihara, Akio: 3 articles (01/2021 - 05/2016)
8.	Kitamura, Takuya: 3 articles (01/2021 - 05/2016)
9.	Sassa, Takayuki: 3 articles (01/2021 - 05/2016)
10.	Golderer, Georg: 3 articles (07/2014 - 06/2010)

Related Diseases

1.	Sjogren-Larsson Syndrome 01/01/2021 - "Mutations in ALDH3A2 cause Sjögren-Larsson syndrome (SLS), a neuro-ichthyotic condition due to the deficiency of fatty aldehyde dehydrogenase (FALDH). " 11/01/2020 - "Sjögren-Larsson syndrome (SLS) is a rare neurometabolic syndrome caused by deficient fatty aldehyde dehydrogenase. " 11/01/2020 - "Neither of the ALDH3A2 alleles in the compound heterozygote patient were able to generate normal fatty aldehyde dehydrogenase, which were likely responsible for her phenotype of Sjögren-Larsson syndrome.Conclusion" 01/01/2020 - "Sjogren Larsson syndrome (SLS) is a rare autosomal recessive inborn error of lipid metabolism due to mutations in the ALDH3A2 that result in a deficiency of fatty aldehyde dehydrogenase (FALDH). " 01/01/2019 - "The Sjögren-Larsson syndrome (SLS) is a rare autosomal recessive disorder caused by pathogenic variants in the ALDH3A2 gene, which codes for fatty aldehyde dehydrogenase (FALDH). "
2.	Ichthyosis (Xeroderma) 09/01/2022 - "Sjögren-Larsson syndrome (SLS) is a neurocutaneous disorder whose causative gene is the fatty aldehyde dehydrogenase ALDH3A2 and of which ichthyosis is the major skin symptom. " 11/01/2019 - "Sjögren-Larsson syndrome is a rare autosomal recessive inborn error of lipid metabolism caused by mutations in the ALDH3A2 gene that codes for fatty aldehyde dehydrogenase and result in a triad of ichthyosis, spasticity, and mental retardation. " 12/01/1999 - "Sjögren-Larsson syndrome (SLS) is an autosomal recessive disorder characterized by ichthyosis, mental retardation, spasticity, and deficient activity of fatty aldehyde dehydrogenase (FALDH). " 01/15/1997 - "Mutations in the fatty aldehyde dehydrogenase (FALDH) gene cause Sjögren-Larsson syndrome (SLS)-a disease characterized by mental retardation, spasticity, and congenital ichthyosis. " 11/01/2020 - "Deficiency in fatty aldehyde dehydrogenase results in an abnormal accumulation of toxic fatty aldehydes in the brain and skin, which cause spasticity, intellectual disability, ichthyosis, and other clinical manifestations. "
3.	Neurocutaneous Syndromes (Phakomatoses) 01/01/2021 - "Sjögren-Larsson syndrome (SLS) is an inherited neurocutaneous disorder whose causative gene encodes the fatty aldehyde dehydrogenase ALDH3A2. " 07/01/2006 - "Sjögren-Larsson syndrome (SLS) is an autosomal recessive neurocutaneous disorder caused by mutation in the ALDH3A2 gene that codes for human fatty aldehyde dehydrogenase (FALDH). " 02/01/2000 - "The Sjögren-Larsson syndrome (SLS) is a severe neurocutaneous disorder due to fatty aldehyde dehydrogenase (FALDH) deficiency. " 09/01/2022 - "Sjögren-Larsson syndrome (SLS) is a neurocutaneous disorder whose causative gene is the fatty aldehyde dehydrogenase ALDH3A2 and of which ichthyosis is the major skin symptom. " 11/01/2020 - "Purpose: Sjögren-Larsson syndrome is a rare, autosomal, recessive neurocutaneous disorder caused by mutations in the ALDH3A2 gene, which encodes the fatty aldehyde dehydrogenase enzyme. "
4.	Intellectual Disability (Idiocy) 11/01/2019 - "Sjögren-Larsson syndrome is a rare autosomal recessive inborn error of lipid metabolism caused by mutations in the ALDH3A2 gene that codes for fatty aldehyde dehydrogenase and result in a triad of ichthyosis, spasticity, and mental retardation. " 12/01/1999 - "Sjögren-Larsson syndrome (SLS) is an autosomal recessive disorder characterized by ichthyosis, mental retardation, spasticity, and deficient activity of fatty aldehyde dehydrogenase (FALDH). " 01/15/1997 - "Mutations in the fatty aldehyde dehydrogenase (FALDH) gene cause Sjögren-Larsson syndrome (SLS)-a disease characterized by mental retardation, spasticity, and congenital ichthyosis. " 11/01/2020 - "Deficiency in fatty aldehyde dehydrogenase results in an abnormal accumulation of toxic fatty aldehydes in the brain and skin, which cause spasticity, intellectual disability, ichthyosis, and other clinical manifestations. " 07/22/2014 - "Mutations in the gene coding for membrane-bound fatty aldehyde dehydrogenase (FALDH) lead to toxic accumulation of lipid species and development of the Sjögren-Larsson Syndrome (SLS), a rare disorder characterized by skin defects and mental retardation. "
5.	Quadriplegia (Spastic Quadriplegia) 04/19/2016 - "Sjögren-Larsson syndrome is a recessively inherited disease caused by a deficiency of fatty aldehyde dehydrogenase with presenting features of congenital ichthyosis, spastic diplegia or tetraplegia, and mental retardation. " 01/15/2012 - "Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive disorder characterized by ichthyosis, spastic di- or tetraplegia and mental retardation due a defect of the fatty aldehyde dehydrogenase (FALDH), related to mutations in the ALDH3A2 gene. " 01/01/2009 - "Sjögren-Larsson syndrome (SLS) is a recessively inherited disease with congenital ichthyosis, spastic diplegia or tetraplegia and mental retardation, caused by a deficiency of fatty aldehyde dehydrogenase. " 01/01/1996 - "Sjögren-Larsson syndrome (SLS, MIM 270200) is a rare autosomal recessive neurocutaneous disorder due to a deficiency of the fatty aldehyde dehydrogenase and defined by a characteristic triad of symptoms including congenital ichthyosis, spastic di- or quadriplegia and mental retardation. " 10/01/2013 - "Sjögren-Larsson syndrome is an inherited disorder of lipid metabolism caused by mutations in the ALDH3A2 gene that codes for fatty aldehyde dehydrogenase, which results in accumulation of fatty aldehydes and alcohols and is characterized by ichthyosis, intellectual disability, and spastic diplegia/quadriplegia. "

Related Drugs and Biologics

1.	Enzymes
2.	Aldehydes
3.	Fatty Acids (Saturated Fatty Acids)
4.	Fatty Alcohols
5.	Alcohols
6.	fatty aldehyde
7.	NAD (NADH)
8.	Proteins (Proteins, Gene)
9.	Oxidoreductases (Dehydrogenase)
10.	Cytoplasmic Dyneins