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CGS 13945 (pentopril)
structure given in first source
Also Known As:
pentopril
; 1-(4-(ethoxycarbonyl)-2-methylpentanoyl)-2,3-dihydroindole-2-carboxylic acid; CGS-13945; 1H-Indole-1-pentanoic acid, 2-carboxy-2,3-dihydro-alpha,gamma-dimethyl-delta-oxo-, alpha-ethyl ester, (2S-(1(alphaS*,gammaS*),2R*))-
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
CGS 13945: 2
Related Diseases
1.
Carcinoma (Carcinomatosis)
12/01/1995 - "
In the present study, we evaluated the effect of the ACE inhibitors captopril and CGS 13945 (10(-8) to 10(-2) M) on proliferation and gene expression in hamster pancreatic duct carcinoma cells in culture.
"
2.
Neoplasms (Cancer)
12/01/1995 - "
Both ACE inhibitors produced a dose-dependent reduction in tumor cell proliferation within 24 hr. Captopril at a concentration of 0.36 mM and CGS 13945 at 150 microM decreased cellular growth rate to approximately half that of the control.
"
3.
Rheumatoid Arthritis
05/01/1990 - "
A clinical and biochemical assessment of a nonthiol ACE inhibitor (pentopril; CGS-13945) in active rheumatoid arthritis.
"
Related Drugs and Biologics
1.
Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)
2.
Captopril (Capoten)
3.
CGS 13945 (pentopril)