|1.||Malkinson, Alvin M: 1 article (08/2002)|
|2.||Kupfer, Rene: 1 article (08/2002)|
|3.||Dwyer-Nield, Lori D: 1 article (08/2002)|
|4.||Thompson, John A: 1 article (08/2002)|
09/15/1998 - "An apoptotic mechanism may underlie the lung tumor promoting actions of BHTOH."
09/15/1998 - "BHTOH is more potent than BHT on an equimolar basis in causing lung damage, enhancing lung tumor development, killing isolated bronchiolar non-ciliated Clara cells, and inhibiting lung epithelial gap junctional intercellular communication. "
06/01/1991 - "The genes that determine whether lung tumor multiplicity is enhanced by chronic BHT exposure may regulate the ability to hydroxylate BHT at a tert-butyl position to form BHT-OH, a metabolite with greater tumor-promoting potency than BHT. "
08/01/2002 - "The downregulaton of calpain II, previously shown to accompany lung tumor promotion by BHT and BHTOH, also occurred with BPPOH. "
08/01/2002 - "Similar differences were found in the doses of BHT, BHTOH, or BPPOH required for tumor promotion after a single initiating dose of 3-methylcholanthrene followed by three weekly injections of the phenol. "
|3.||Body Weight (Weight, Body)
08/01/2002 - "The conversions of BPPOH and BHTOH to quinone methides in lung microsomes from male BALB/cByJ mice were quantitatively similar, but in vivo the former was pneumotoxic at one-half of the dose required for the latter and one-eighth of the dose required for BHT, as determined by increased lung weight:body weight ratios following a single i.p. "
|1.||Butylated Hydroxytoluene (BHT)
|2.||Phenol (Carbolic Acid)