|1.||Aziz, Farookh: 1 article (04/2015)|
|2.||Patil, Prashant: 1 article (04/2015)|
|3.||Bhat, Rukhmi V: 1 article (01/2003)|
|4.||Deshmukh, C T: 1 article (01/2003)|
|5.||Weinshilboum, Richard M: 1 article (10/2002)|
|6.||Johnson, Kenneth L: 1 article (10/2002)|
|7.||Wood, Thomas C: 1 article (10/2002)|
|8.||Naylor, Stephen: 1 article (10/2002)|
|1.||Hypoprothrombinemias (Prothrombin Deficiency)
02/01/1997 - "There are three proposed mechanisms of cephalosporin-associated hypoprothrombinemia, two of which involve the N-methylthiotetrazole (NMTT) chain. "
06/01/1986 - "Cephalosporin-induced hypoprothrombinemia: is the N-methylthiotetrazole side chain the culprit?"
01/01/2003 - "Hypoprothrombinemia previously reported to be due to B-lactam antibiotics containing the N-Methyl Thio Tetrazole (NMTT) group also resulted from antibiotics without this side chain. "
01/01/1990 - "Cephalosporin antibiotics with N-methyl-thio-tetrazole (NMTT) side chains have been known to be associated with the development of hypoprothrombinemia. "
06/01/1989 - "The N-methylthiotetrazole side chain (NMTT) that is present on several cephalosporins has been implicated in the development of antibiotic-associated hypoprothrombinemia. "
01/01/1992 - "A prospective surveillance program was initiated to determine the relative role of antibiotics containing N-methylthiotetrazole (NMTT) versus patient risk factors in producing antibiotic-associated bleeding. "
12/01/1988 - "Spontaneous reports of bleeding: comparison of N-methylthiotetrazole side chain (MTT) and non-MTT cephalosporins."
10/01/2002 - "Cephalosporin antibiotics with structures that include the heterocyclic leaving group 1-methyltetrazole-5-thiol (MTT) can cause hypoprothrombinemia and hemorrhage as a result of MTT-dependent inhibition of the gamma-carboxylation of glutamate. "
01/01/1991 - "The effect of flomoxef, a newly developed oxacephem antibiotic with an N-hydroxyethyltetrazolethiol (HTT) side chain, on blood coagulation and alcohol metabolism was compared with that of a series of cephalosporin antibiotics with N-methyltetrazolethiol (NMTT), thiadiazolethiol (TDT) or methylthiadiazolethiol (MTDT) side chains in position 3' of the cephalosporin nucleus known to cause hypoprothrombinemia and bleeding in patients who are malnourished, debilitated and/or of high age. "
|3.||Urinary Tract Infections (Urinary Tract Infection)
09/01/1989 - "The mechanism of hypoprothrombinemia induced by cephalosporins containing the N-methylthiotetrazole (NMTT) side chain has been investigated in a randomized clinical, trial (pilot study) with 14 hospitalized patients (main inclusion criteria: age greater than or equal to 50 years, urinary tract infection, normal prothrombin time. "
|4.||Protein-Energy Malnutrition (Marasmus)
|1.||Cephalosporins (Cephalosporin Antibiotics)
|2.||Anti-Bacterial Agents (Antibiotics)
|3.||Glutamic Acid (Glutamate)
|4.||NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
|6.||Gonadal Steroid Hormones (Sex Hormones)
|9.||Cefoperazone (Cefoperazone Sodium)