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NAD+ synthase

consider also EC 6.3.5.1

Also Known As:

NAD synthase; NAD synthetase

Networked: 14 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Ligases: 5553
    - Carbon-Nitrogen Ligases
      - Amide Synthases
        NAD+ synthase: 14

Experts

1.	Zhai, R Grace: 4 articles (12/2021 - 11/2006)
2.	Li, Chong: 2 articles (12/2021 - 01/2020)
3.	Liu, Jiaqi: 2 articles (12/2021 - 01/2020)
4.	Ruan, Kai: 2 articles (12/2021 - 01/2012)
5.	Zhu, Yi: 2 articles (12/2021 - 01/2020)
6.	Diaz-Perez, Zoraida: 1 article (12/2021)
7.	Rai, Priyamvada: 1 article (12/2021)
8.	Tao, Xianzun: 1 article (12/2021)
9.	Wang, Hongbo: 1 article (12/2021)
10.	Camacho, Cristel V: 1 article (01/2021)

Related Diseases

1.	Wallerian Degeneration 11/01/2006 - "Wallerian degeneration slow (Wld(s)) mice overexpress a chimeric protein containing the NAD synthase NMNAT (nicotinamide mononucleotide adenylyltransferase 1) and exhibit a delay in axonal degeneration. " 10/01/2011 - "Recent studies have found that the activity of the nicotinamide adenine dinucleotide (NAD) synthase enzyme, nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) can affect the rate of Wallerian degeneration in mice and drosophila. "
2.	Frontotemporal Dementia (Semantic Dementia) 01/15/2012 - "Here, we use a Drosophila model of frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17), in order to study the neuroprotective capacity of a recently identified neuronal maintenance factor, nicotinamide mononucleotide (NAD) adenylyl transferase (NMNAT), a protein that has both NAD synthase and chaperone function. "
3.	Tuberculosis (Tuberculoses) 04/01/2009 - "tuberculosis NAD(+) synthetase. " 08/01/2002 - "tuberculosis NAD(+) synthetase. "
4.	Neoplasms (Cancer) 11/17/2022 - "It plays an important role in tumor cell proliferation, acting concurrently as an nicotinamide adenine dinucleotide (NAD+) synthase and, unexpectedly, as an extracellular signaling molecule for several tumor-promoting pathways. " 12/17/2021 - "Here, we adapted a Drosophila glial neoplasia model and discovered the genetic requirement for NAD+ synthase nicotinamide mononucleotide adenylyltransferase (NMNAT) in glioma progression in vivo and in human glioma cells. "
5.	Tauopathies 01/01/2020 - "Here, we report that nicotinamide mononucleotide adenylyltransferase (NMNAT), a well-known NAD+ synthase, serves as a chaperone of pTau to prevent its amyloid aggregation in vitro as well as mitigate its pathology in a fly tauopathy model. "

Related Drugs and Biologics

1.	NAD (NADH)
2.	Nicotinamide-Nucleotide Adenylyltransferase
3.	Enzymes
4.	Proteins (Proteins, Gene)
5.	Nicotinamide Mononucleotide
6.	glutamine-synthetase adenylyltransferase
7.	Nicotinamide Phosphoribosyltransferase
8.	Vitamin D-Binding Protein
9.	Superoxide Dismutase
10.	Glutathione Peroxidase