curdlan

01/01/2021 - "Studies on the mechanism of action of curdlan-induced suppression in microbial and tumor cells at the cellular and molecular levels would not only enhance our understanding regarding the therapeutic effectiveness of curdlan but also help in the discovery of new drugs and dietary supplements. "
01/01/2016 - "In this study, we investigated the effect of curdlan on MDSCs and found that curdlan could promote MDSCs to differentiate into a more mature state and then significantly reduce the suppressive function of MDSCs, decrease the MDSCs in vivo and down-regulate the suppression in tumor-bearing mice, thus leading to enhanced anti-tumor immune responses. "
05/28/2018 - "Curdlan is found to inhibit tumors and its sulfated derivative possess anti-HIV activity. "
10/01/2016 - "Curdlan increased antitumor activity of DCs in a syngeneic tumor model. "
01/01/2016 - "We, therefore, increase the understanding of further mechanisms by which curdlan achieves anti-tumor effects."

05/20/2023 - "Furthermore, when the instant film encountered the water vapor at 50 °C, it almost completely disintegrated after immersion for 30 min. The results indicate that the electrospun PEO/curdlan nanofiber film is highly feasible for biomedical applications consisting of instant masks and quick-release wound dressings, even in the water vapor environment."
04/30/2023 - "In brief, the results advocate agarose-curdlan mat as a potential multifunctional, bioactive, and eco-friendly dressing for healing diabetic wounds."
03/28/2022 - "Ag-Contained Superabsorbent Curdlan-Chitosan Foams for Healing Wounds in a Type-2 Diabetic Mice Model."
08/11/2021 - "These results validate the further development of Curdlan/AgNPs nanofibril hydrogels in clinical wound management."
05/01/2021 - "Superabsorbent curdlan-based foam dressings with typical hydrocolloids properties for highly exuding wound management."

03/15/2013 - "Curdlan eliminated the liver and spleen parasite burden in a 45-day BALB/c mouse model of visceral leishmaniasis at a dosage of 10 mg/kg/day as determined by Giemsa-stained organ impression smears. "
03/15/2013 - "Successful therapy of visceral leishmaniasis with curdlan involves T-helper 17 cytokines."
03/15/2013 - "The aim of this study was to evaluate and characterize the therapeutic potential of curdlan, a naturally occurring β-glucan immunomodulator, against visceral leishmaniasis, a fatal parasitic disease. "

01/01/2014 - "Curdlan β-1,3-glucooligosaccharides induce the defense responses against Phytophthora infestans infection of potato (Solanum tuberosum L. "
01/01/2023 - "Next, Mongolian gerbils were intranasally immunized with curdlan plus VP1, and they had effective protection against EV71 C4a infection, while decreasing viral infection and tissue damage by inducing Th17 responses. "
01/01/2014 - "Although several elicitors were used to induce the resistance of potato plant to microbial pathogen infection, the role of curdlan oligosaccharide (CurdO) has not been established. "
11/03/2020 - "In a model of intranasal administration of whole cell vaccines (WCVs) with the adjuvant curdlan, we examined local and systemic immune responses following infection. "
01/01/2018 - "Based on these findings, we evaluated the impact of Curdlan/Dectin-1 interactions in experimental leishmaniasis and were able to demonstrate that the presence of Curdlan at the site of infection modulates the course of disease in BALB/c mice: wild-type BALB/c mice treated intradermally with Curdlan developed a protective immune response against L. "

09/01/2012 - "We measured antibody and Th17 responses after intranasal immunization of mice with the purified proteins mixed with the Th17 adjuvant curdlan, and we tested the protective efficacy of vaccination in a murine model of acute pneumonia. "
01/01/2018 - "At 20 weeks post-injection, curdlan-treated SKG mice developed not only arthritis but also lung inflammation combined with fibrosis, which was identified by PET-MRI and histological analysis. "
11/12/2018 - "These PopB/PcrH-curdlan vaccines protect mice against acute lethal pneumonia in an IL-17-dependent fashion involving CD4 helper T cells secreting IL-17 (Th17 cells). "