|1.||Benham, Helen: 3 articles (10/2014 - 07/2012)|
|2.||Velasco, Jared: 3 articles (10/2014 - 07/2012)|
|3.||Ruutu, Merja: 3 articles (10/2014 - 07/2012)|
|4.||Thomas, Ranjeny: 3 articles (10/2014 - 07/2012)|
|5.||McGuckin, Michael A: 3 articles (10/2014 - 07/2012)|
|6.||Miller, J D: 3 articles (10/2013 - 03/2010)|
|7.||Rand, Thomas G: 3 articles (10/2013 - 03/2010)|
|8.||Clowers, Jenna S: 2 articles (01/2015 - 07/2011)|
|9.||Rosenzweig, Holly L: 2 articles (01/2015 - 07/2011)|
|10.||Sakaguchi, Shimon: 2 articles (01/2015 - 03/2005)|
|1.||Visceral Leishmaniasis (Kala Azar)
03/15/2013 - "Curdlan eliminated the liver and spleen parasite burden in a 45-day BALB/c mouse model of visceral leishmaniasis at a dosage of 10 mg/kg/day as determined by Giemsa-stained organ impression smears. "
03/15/2013 - "The aim of this study was to evaluate and characterize the therapeutic potential of curdlan, a naturally occurring β-glucan immunomodulator, against visceral leishmaniasis, a fatal parasitic disease. "
03/15/2013 - "Successful therapy of visceral leishmaniasis with curdlan involves T-helper 17 cytokines."
09/01/2012 - "Curdlan is a linear (1→3)-β-glucan and has shown activity against tumors and infectious agents. "
03/06/2015 - "The novel curdlan-based nanoparticles efficiently delivered siRNAs to human cancer cells and mouse primary cells, and reduced 70-90% of target mRNA level. "
10/01/2009 - "Curdlan derivatives able to enhance cytostatic drugs activity on tumor cells."
03/01/1998 - "The activity inducing tumor regressing factor of the glucan derivatives was stronger than a linear (1-->3)-beta-D-glucan (curdlan)."
02/01/1984 - "An aminated beta-1,3-D-glucan derivative of curdlan is reported to render macrophages cytostatic to L-929 cells and to potentiate macrophage cytotoxicity to the tumor cells in vitro."
12/15/2012 - "In this study, we examined the effect of curdlan, a linear β-(1-3)-glucan, on the development of allergic airway inflammation. "
10/01/2014 - "Curdlan triggered acute inflammation regardless of the presence of the SKG allele or microbiota. "
12/15/2012 - "Taken together, these results suggest that curdlan is capable of inducing IL-10-producing CD4(+) T cells and inhibiting the development of eosinohilic airway inflammation, underscoring the therapeutic potential of curdlan for allergic diseases."
12/15/2012 - "β-glucan curdlan induces IL-10-producing CD4+ T cells and inhibits allergic airway inflammation."
03/01/2010 - "Collectively, these results confirm the inflammatory nature of curdlan and demonstrate the complex of inflammation-associated gene responses induced by (1-3)-beta-D glucan in triple helical forms. "
10/01/2000 - "Interestingly, two sulfated derivatives synthesized from the alpha-(1-->3)-D-glucan and curdlan, a beta-(1-->3)-D-glucan, all had significant higher antitumor activity against Ehrlich ascites carcinoma (EAC) than the originals. "
10/01/2009 - "The aim of this study was to investigate the capacity of six Curdlan (beta-glucan) derivatives to up-regulate the Doxorubicin, Actinomycin D and Cyclophophamide cytostatic drug activity on tumor cells (murine B16 melanoma and human HEp-2 laryngeal carcinoma cell lines). "
|2.||Proteins (Proteins, Gene)
|3.||Sulfates (Sulfates, Inorganic)
|4.||Drug Therapy (Chemotherapy)