|1.||Jiang, Haobo: 7 articles (01/2014 - 11/2003)|
|2.||Wang, Yang: 5 articles (10/2007 - 11/2003)|
|3.||Söderhäll, Kenneth: 3 articles (04/2012 - 05/2003)|
|4.||Kanost, Michael R: 3 articles (04/2005 - 11/2003)|
|5.||Konrad, Matthias: 2 articles (01/2015 - 01/2012)|
|6.||Cremer, Sylvia: 2 articles (01/2015 - 01/2012)|
|7.||Tragust, Simon: 2 articles (01/2015 - 01/2012)|
|8.||Arockiaraj, Jesu: 2 articles (07/2013 - 02/2012)|
|9.||Charoensapsri, Walaiporn: 2 articles (04/2013 - 07/2009)|
|10.||Tassanakajon, Anchalee: 2 articles (04/2013 - 07/2009)|
12/21/1999 - "In our study we used Anopheles gambiae, the most important human malaria vector, to characterize the first arthropod prophenoloxidase gene at the genomic level. "
12/21/1999 - "In mosquitoes, prophenoloxidase has been shown to be involved in refractory mechanisms against malaria parasites. "
04/23/1999 - "A hemocyte-like cell line established from the malaria vector Anopheles gambiae expresses six prophenoloxidase genes."
01/01/2014 - "We found both nitroquine in the blood meal and Plasmodium infection altered transcription of mosquito genes implicated in diverse processes, including pathogen recognition, signal transduction, prophenoloxidase activation, cytoskeleton assembling, cell adhesion, and oxidative stress. "
02/01/2013 - "In mosquitoes, serpins (SRPNs) regulate the activation of prophenoloxidase and thus melanization, contribute to malaria parasite lysis, and likely Toll pathway activation. "
04/01/2015 - "In insects, this goal is generally reached by spectrophotometrically measuring (pro-) phenoloxidase activity, an enzymatic and non-specific process activated after wounding and parasite infections. "
08/01/2014 - "Immune responses of prophenoloxidase in the mud crab Scylla paramamosain against Vibrio alginolyticus infection: in vivo and in vitro gene silencing evidence."
05/01/2014 - "Prophenoloxidase activation is required for survival to microbial infections in Drosophila."
05/01/2014 - "Based on an increased PO activity of crab hemolymph during the course of White Spot Syndrome Virus (WSSV) infection, these results suggest that prophenoloxidase pathway was employed for host defense mechanism against WSSV and it may link to the role of large granular hemocyte. "
01/01/2014 - "We also provide further evidence for the existence of a functional link between TEP1 and activation of hemolymph prophenoloxidase during systemic infections. "
|3.||Wounds and Injuries (Trauma)
03/01/2002 - "The hemocytes lysed and released granular materials around the wound site, prophenoloxidase being mostly localized in granules and cuticle. "
03/01/2002 - "Immunocytochemical localization showed that prophenoloxidase (pro-PO) was distributed in the wound site. "
09/01/2012 - "Insect prophenoloxidase (PPO) is a key enzyme that induces melanization around invading pathogens and at wounds to prevent further infection. "
01/22/2015 - "Ants with high Laboulbenia levels showed significantly longer self-grooming and elevated expression of immune genes relevant for wound repair and antifungal responses (β-1,3-glucan binding protein, Prophenoloxidase), compared with ants carrying low Laboulbenia levels. "
04/20/2012 - "Here we show that the melanization of hindgut content induced by prophenoloxidase, a key enzyme that induces the production of melanin around invaders and at wound sites, is the last line of immune defense to clear bacteria before feces excretion. "
|4.||Bacterial Infections (Bacterial Infection)
01/01/2008 - "Levels of the immunity factors prophenoloxidase and apismin are positively correlated with development, while others surprisingly were not significantly age-regulated, suggesting a molecular explanation for why bees are susceptible to major age-associated bee bacterial infections such as American Foulbrood or fungal diseases such as chalkbrood. "
01/01/2006 - "Based on the above, we propose that although NO production is involved in cellular immune responses of this insect to bacterial infection it does not appear to be a part of the signalling pathway that initiates the prophenoloxidase (PPO) cascade, and the extended NO production/overproduction by pharate prepupal hemocytes could result in cytotoxic rather than cytoprotective effects compared with larval hemocytes."
01/01/2010 - "We found that the infection was associated with a general decrease of the prophenoloxidase activity, haemocyte density, resistance to an artificial bacterial infection and level of sugar reserves in G. "
01/01/2007 - "The link between hemolin and the prophenoloxidase system suggests that hemolin is a pattern recognition protein important for the triggering of the prophenoloxidase cascade in the defence against bacterial infections."
|5.||Contagious Ecthyma (Orf)
07/25/2013 - "rosenbergii prophenoloxidase (MrProPO) consists of 3378 base pairs (bp) with an open reading frame (ORF) of 2099 bp. This ORF encoded a polypeptide of 700 amino acids (aa) with an estimated molecular mass of 80 kDa and a predicted isoelectric point (pI) of 6.7. "
05/01/2009 - "The full-length cDNA of prophenoloxidase gene consists of 3040 bp with a 2061 bp Open Reading Frame (ORF), encoding 686 amino acids. "
|1.||Serine Proteases (Serine Protease)
|2.||Monophenol Monooxygenase (Tyrosinase)
|3.||Complementary DNA (cDNA)
|4.||Messenger RNA (mRNA)
|6.||HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)
|8.||Proteins (Proteins, Gene)
|9.||Peptide Hydrolases (Proteases)