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bis(tetraphenylphosphonium)tetracyanato- bis- 4- methoxy- 4- phenyltellurate(IV) (TTMT)

organo-tellurium cpd used in Te toxicity studies

Also Known As:

TTMT; Phosphonium, tetraphenyl-, tetrakis(cyanato-N)bis(4-methoxyphenyl)tellurate(2-) (2:1)

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Elements: 18681
  - Metalloids: 199
    - Tellurium: 142
      - bis(tetraphenylphosphonium)tetracyanato-bis-4-methoxy-4-phenyltellurate(IV): 1
  - Chalcogens: 3
    - Tellurium: 142
      - bis(tetraphenylphosphonium)tetracyanato-bis-4-methoxy-4-phenyltellurate(IV): 1

Related Diseases

1.

Body Weight (Weight, Body)

05/01/1983 - "These compounds, at 2 and 1 mg Te/kg body weight as TTMT and TACT, respectively, produced cholinergic signs and caused death within 3 days. "
05/01/1983 - "Administration at maximum tolerable doses of 0.5 mg and 0.1 mg Te/kg body weight as TTMT and TACT, respectively, resulted in significant reduction of acetylcholine esterase (AChE) and monoamine oxidase (MAO) in serum and brain and by a significant decrease in hepatic glutathione and in glutathione-S-transferase (GST) and alkaline phosphatase in liver and kidney."

Related Drugs and Biologics

1.	Monoamine Oxidase (MAO)
2.	Glutathione Transferase (Glutathione S-Transferase)
3.	Glutathione (Reduced Glutathione)
4.	Esterases
5.	Alkaline Phosphatase
6.	Acetylcholine (Acetylcholine Chloride)
7.	Cholinergic Agents (Cholinergics)