hirsutine

isolated from Uncaria rhynchophylla; RN given refers to (3beta,16E)-isomer

Also Known As:

18,19-dihydrocorynantheine; corynantheidine; dihydrocorynantheine; hirsutine, (16E)-isomer; hirsutine, (16E,20beta)-isomer; hirsutine, (3beta,16E)-isomer

Networked: 18 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - hirsutine: 18

Experts

1.	Hayakawa, Yoshihiro: 3 articles (07/2016 - 11/2014)
2.	Lou, Chenghua: 3 articles (07/2016 - 11/2014)
3.	Saiki, Ikuo: 3 articles (07/2016 - 11/2014)
4.	Zhu, Yi Zhun: 2 articles (01/2022 - 01/2011)
5.	Yokoyama, Satoru: 2 articles (07/2016 - 04/2015)
6.	Ding, Qian: 1 article (01/2022)
7.	Hu, Wei: 1 article (01/2022)
8.	Lei, Heping: 1 article (01/2022)
9.	Li, Meng: 1 article (01/2022)
10.	Li, Qixiu: 1 article (01/2022)

Related Diseases

1.	Myocardial Ischemia (Ischemic Heart Diseases) 12/31/2023 - "Hirsutine ameliorates myocardial ischemia-reperfusion injury through improving mitochondrial function via CaMKII pathway."
2.	Reperfusion Injury 12/31/2023 - "Hirsutine ameliorates myocardial ischemia-reperfusion injury through improving mitochondrial function via CaMKII pathway."
3.	Insulin Resistance 01/01/2022 - "Hirsutine ameliorates hepatic and cardiac insulin resistance in high-fat diet-induced diabetic mice and in vitro models."
4.	Hyperglycemia 01/01/2022 - "Hirsutine administration for 8 weeks improved HFD-induced peripheral hyperglycemia, glucose tolerance and IR by OGTT and ITT assays, and simultaneously attenuated hepatic steatosis and cardiac hypertrophy by pathological observation. "
5.	Cardiomegaly (Heart Hypertrophy) 01/01/2022 - "Hirsutine administration for 8 weeks improved HFD-induced peripheral hyperglycemia, glucose tolerance and IR by OGTT and ITT assays, and simultaneously attenuated hepatic steatosis and cardiac hypertrophy by pathological observation. "

Related Drugs and Biologics

1.	Calcium-Calmodulin-Dependent Protein Kinase Type 2
2.	Glucose (Dextrose)
3.	Phytochemicals
4.	Adenosine Triphosphate (ATP)
5.	Cytochromes c (Cytochrome c)
6.	Phosphotransferases (Kinase)
7.	Enzymes
8.	Antioxidants
9.	Alkaloids
10.	hirsuteine

Related Therapies and Procedures

1.	Therapeutics
2.	Chinese Traditional Medicine (Traditional Chinese Medicine)