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5-hydroxy-6-methoxyindole

from supernatant of melanoma cell culture

Also Known As:

5H6MI

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - 5-hydroxy-6-methoxyindole: 3

Related Diseases

1.	Melanoma (Melanoma, Malignant) 01/01/1983 - "In the supernatant of melanoma cell culture SK mel 25 three indolic compounds - 5-hydroxy-6-methoxyindole, 5-hydroxy-6-methoxyindolyl-2-carboxylic, and 6-hydroxy-5-methoxyindolyl-2-carboxylic acids - have been identified. " 01/01/1983 - "Using gas chromatography--mass spectrometry we were able to identify five indolic compounds in the urine of melanoma patients: 5,6-dihydroxyindole (5,6DHI), 5-hydroxy-6-methoxyindole (5H6MI), 6-hydroxy-5-methoxyindole (6H5MI), and 5-hydroxy-6-methoxyindolyl-2-carboxylic (5H6MI2C) and 6-hydroxy-5-methoxyindolyl-2-carboxylic acids (6H5MI2C). "
2.	Oculocutaneous Albinism (Albinism, Yellow Mutant) 07/01/1987 - "We measured the urinary excretion of 3,4-dihydroxyphenylalanine (dopa), 5-S-cysteinyldopa (5-S-CD), and 2 indolic compounds, namely 5-hydroxy-6-methoxyindole (5H6MI) and 5-hydroxy-6-methoxyindole-2-carboxylic acid (5H6MI2C) in urine samples of 4 groups of people with different contents of cutaneous melanin: Asian group, white group, and 2 groups of whites 1 with vitiligo and 1 with tyrosinase-negative oculocutaneous albinism. "
3.	Vitiligo 07/01/1987 - "We measured the urinary excretion of 3,4-dihydroxyphenylalanine (dopa), 5-S-cysteinyldopa (5-S-CD), and 2 indolic compounds, namely 5-hydroxy-6-methoxyindole (5H6MI) and 5-hydroxy-6-methoxyindole-2-carboxylic acid (5H6MI2C) in urine samples of 4 groups of people with different contents of cutaneous melanin: Asian group, white group, and 2 groups of whites 1 with vitiligo and 1 with tyrosinase-negative oculocutaneous albinism. "

Related Drugs and Biologics

1.	5-hydroxy-6-methoxyindole
2.	Acids
3.	5-hydroxy-6-methoxy-2-indolylcarboxylic acid (HMICA)
4.	Monophenol Monooxygenase (Tyrosinase)
5.	Melanins (Melanin)
6.	Dihydroxyphenylalanine (Dopa)
7.	Cysteinyldopa
8.	6-hydroxy-5-methoxyindole
9.	5,6-dihydroxyindole
10.	6-hydroxy-5-methoxy-2-indolylcarboxylic acid