|1.||McCormick, Beth A: 6 articles (12/2011 - 05/2004)|
|2.||Hurley, Bryan P: 4 articles (02/2015 - 05/2004)|
|3.||Gronert, Karsten: 3 articles (02/2015 - 12/2008)|
|4.||Mumy, Karen L: 3 articles (12/2011 - 12/2008)|
|5.||Nigam, Santosh: 3 articles (06/2011 - 03/2003)|
|6.||Siccardi, Dario: 3 articles (12/2008 - 05/2004)|
|7.||Mrsny, Randall J: 3 articles (12/2008 - 05/2004)|
|8.||Pirzai, Waheed: 2 articles (02/2015 - 02/2011)|
|9.||Bien, Jeffrey D: 2 articles (12/2011 - 12/2008)|
|10.||Zafiriou, Maria-Patapia: 2 articles (06/2011 - 01/2008)|
12/01/2008 - "Moreover, using multiple in vitro and in vivo models, we show that induction of intestinal inflammation profoundly up-regulates apical expression of MRP2, and that interfering with hepoxilin A(3) synthesis and/or inhibition of MRP2 function results in a marked reduction in inflammation and severity of disease. "
12/01/2008 - "Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3."
07/01/2007 - "Thus, the objective of this review was to highlight the recent findings that implicate hepoxilin A(3) as a key regulator of mucosal inflammation."
05/11/2004 - "Our studies not only identify this factor, previously termed pathogen-elicited epithelial chemoattractant, as the eicosanoid hepoxilin A(3) (hepA(3)) but also demonstrate that it is a key factor promoting the final step in PMN recruitment to sites of mucosal inflammation. "
01/01/2014 - "Among endogenous TRPA1 agonists that have been shown to play a role in the pathogenesis of pain and inflammatory conditions are, for example, methylglyoxal, 4-hydroxynonenal, 12-lipoxygenase-derived hepoxilin A3, 5,6-epoxyeicosatrienoic acid and reactive oxygen species, while mustard oil and cinnamaldehyde are most commonly used exogenous TRPA1 agonists in experimental studies. "
02/01/2015 - "Hepoxilin A3 (HXA3) is a chemotactic eicosanoid shown to mediate the transepithelial passage of neutrophils in response to infection in several model systems and at multiple mucosal surfaces. "
02/01/2011 - "The eicosanoid hepoxilin A(3) is a potent neutrophil chemoattractant produced by epithelial cells in response to infection with P. "
12/01/2011 - "Typhimurium infection the multidrug resistance-associated protein 2 (MRP2) is highly expressed at the apical surface of the intestinal epithelia, and that it functions as an efflux pump for the potent neutrophil chemoattractant hepoxilin A(3) . "
06/01/2011 - "Our previous work showed that, in the absence of cytosolic GPx in insulinoma RINm5F cells, an intrinsic activity of 12 lipoxygenase (12(S)-LOX) converts 12S-hydroperoxyeicosatetraenoic acid (12(S)-HpETE) to the bioactive epoxide hepoxilin A(3) (HXA(3)). "
03/13/2003 - "Interestingly, we found that the rat insulinoma RINm5F cells, which are devoid of cytoplasmic glutathione peroxidase (cGPx)/phospholipid hydroperoxide glutathione peroxidase (PHGPx), produce solely hepoxilin A(3) (HXA(3)). "
|5.||Spinal Cord Injuries (Spinal Cord Injury)
|1.||Reactive Oxygen Species (Oxygen Radicals)
|3.||pathogen-elicited epithelial chemoattractant
|6.||cinnamic aldehyde (cinnamaldehyde)
|7.||Staphylococcal Protein A (A, Protein)
|10.||Arachidonate 12-Lipoxygenase (12 Lipoxygenase)