NSC 251635

Also Known As:

2-(3'-(methoxycarbonylamino)phenyl)-3-phenyl-6-methoxycarbonylamino-4-(3H)-quinazolone; NSC-251635; Carbamic acid, (3-(3,4-dihydro-6-((methoxycarbonyl)amino)-4-oxo-3-phenyl-2-quinazolinyl)phenyl)-, methyl ester

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - NSC 251635: 3

Related Diseases

1.	Neoplasms (Cancer) 11/01/1983 - "Five patients with advanced multiresistant neoplasms were infused with NSC-251635 (a water-insoluble antimitotic agent) entrapped in egg yolk lecithin, cholesterol, and stearylamine liposomes. " 05/01/1986 - "In patients with resistant malignant tumors, we performed a pilot trial of intravenous infusion of a water-insoluble cytostatic agent, NSC 251635, entrapped in large volumes of liposomes made of egg yolk lecithin, cholesterol, and stearylamine (4:3:1). "
2.	Leukemia L1210 06/01/1983 - "In vivo, after ip or iv injections to CDF1 mice bearing intraperitoneal or intravenous L1210 leukemia, NSC-251635 was active only when it was incorporated in the liposomes and not when it was given as a suspension in Klucel or in saline. "

Related Drugs and Biologics

1.	Liposomes (Liposome)
2.	Lecithins
3.	Cholesterol
4.	stearylamine
5.	Cytostatic Agents
6.	Antimitotic Agents
7.	Suspensions

Related Therapies and Procedures

1.	Intravenous Infusions
2.	Injections