|1.||Takeuchi, Makoto: 2 articles (11/2006 - 01/2004)|
|2.||Taniguchi, Naoyuki: 1 article (01/2015)|
|3.||Kizuka, Yasuhiko: 1 article (01/2015)|
|4.||Rehder, Douglas S: 1 article (03/2013)|
|5.||Borges, Chad R: 1 article (03/2013)|
|6.||Boffetta, Paolo: 1 article (03/2013)|
|7.||Minowa, Mari T: 1 article (11/2006)|
|8.||Yoshida, Aruto: 1 article (11/2006)|
|9.||Oguri, Suguru: 1 article (11/2006)|
|10.||Nofrate, Valentina: 1 article (06/2005)|
10/08/1999 - "This supposition was confirmed by molecular biological study of GnT-IV in placenta and choriocarcinoma cell lines. "
08/15/1999 - "On the basis of these results, we proposed that ectopic expression of GnT-IVa gene should occur along with the malignancy of trophoblastic tissues, and that the increased GnT-IV activity should be the main cause of the formation of abnormal biantennary sugar chains in choriocarcinoma. "
08/15/1999 - "GnT-IV activities in choriocarcinoma cell lines were increased from 16- to 66-fold and GnT-III activity was increased from 15- to 25-fold as compared with those in human placentae, whereas other enzyme activities were not increased significantly. "
11/01/1988 - "The altered glycosylation of hCG is brought about by the ectopic expression of N-acetylglucosaminyltransferase IV. With use of this altered glycosylation, a novel method useful for the diagnosis of choriocarcinoma was established."
01/01/2004 - "To confirm this, we measured the N-acetylglucosaminyltransferase (GnT)-IV activity and hCG productivity in three choriocarcinoma cell lines, and selected JEG-3 cells. "
06/10/2005 - "The gene encoding for mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetyl-glucosaminyl-transferase (GnT-IV) became significantly upregulated in primary/metastatic tumor pairs (p < 0.001). "
08/15/1999 - "Among the two GnT-IV genes found in human tissues only GnT-IVa gene was strongly expressed in the cancer cells: from three to seven times as much as in the normal tissue, whereas that of GnT-IVb remained constant. "
01/01/2015 - "In addition to these enzymes, GnT-IV and GnT-IX (GnT-Vb) will be also discussed in relation to cancer. "
11/01/2006 - "Two human GnT-IV isozymes (GnT-IVa and GnT-IVb) had been identified, which exhibit different expression profiles among human tissues and cancer cell lines. "
05/01/1988 - "The malignant transformational change of the sugar moiety of hCG can be explained by an increase of a fucosyltransferase, which forms the Fuc alpha 1----6GlcNAc group and by ectopic expression and subsequent modification of N-acetylglucosaminyltransferase IV. The appearance of tumor-specific sugar chains of hCG has been used to develop a new diagnostic method for invasive mole and choriocarcinoma."
|3.||Pancreatic Neoplasms (Pancreatic Cancer)
11/17/2000 - "The primary structure was found to be significantly similar to human GnT IV-homologue, the gene for which was cloned from the deleted region in pancreatic cancer, and to human and bovine GnT IVs. "
01/01/1999 - "A novel human gene determining a polypeptide product of 478 residues with an estimated molecular mass of 55 kDa, which has significant homology and structural similarity to Bos UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase (GnT-IV), was cloned from the commonly deleted region in pancreatic cancer at 12q21. "
|4.||Lung Neoplasms (Lung Cancer)
|5.||Hepatocellular Carcinoma (Hepatoma)
|5.||Uridine Diphosphate (UDP)
|10.||N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase)