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phenylenediamine mustard

RN given refers to parent cpd

Also Known As:

phenylenediamine mustard monohydrochloride

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Mustard Compounds: 3
      - Nitrogen Mustard Compounds: 2
        phenylenediamine mustard: 3

Experts

1.	Backmann, Natalija: 1 article (04/2004)
2.	Cortez-Retamozo, Virna: 1 article (04/2004)
3.	De Baetselier, Patrick: 1 article (04/2004)
4.	Muyldermans, Serge: 1 article (04/2004)
5.	Revets, Hilde: 1 article (04/2004)
6.	Senter, Peter D: 1 article (04/2004)
7.	Wernery, Ullrich: 1 article (04/2004)

Related Diseases

1.	Neoplasms (Cancer) 05/01/1983 - "The prodrug of phenylenediamine mustard was also slightly less toxic than the parent drug, but again there was no evidence for an improved therapeutic index against the B16 tumor." 04/15/2004 - "In vitro experiments showed that the nanobody-enzyme conjugate effectively activated the release of phenylenediamine mustard from the cephalosporin nitrogen mustard prodrug 7-(4-carboxybutanamido) cephalosporin mustard at the surface of carcinoembryonic antigen-expressing LS174T cancer cells. "
2.	Carcinoma (Carcinomatosis) 11/01/1999 - "Results from in vitro experiments using two lung carcinoma cell lines demonstrated that the conjugates were equally active in effecting the release of phenylenediamine mustard from the cephalosporin nitrogen mustard prodrug CCM. "

Related Drugs and Biologics

1.	Prodrugs
2.	Mechlorethamine (Nitrogen Mustard)
3.	Cephalosporins (Cephalosporin Antibiotics)
4.	Enzymes
5.	Carcinoembryonic Antigen
6.	cephalosporin mustard