|1.||Park, Won Sun: 1 article (03/2015)|
|2.||Park, Sae-Gwang: 1 article (03/2015)|
|3.||Jung, Won-Kyo: 1 article (03/2015)|
|4.||Lee, Chang-Min: 1 article (03/2015)|
|5.||Choi, Il-Whan: 1 article (03/2015)|
|6.||Yang, Jae-Wook: 1 article (03/2015)|
|7.||Seo, Su-Kil: 1 article (03/2015)|
|8.||Lee, Young-Min: 1 article (03/2015)|
|9.||Na, Giyoun: 1 article (03/2015)|
|10.||Lee, Dae-Sung: 1 article (03/2015)|
03/01/1986 - "To determine the possible in vivo role of PAF in inflammation, we examined the effects of the PAF antagonist and structural analogue, CV3988 on acute inflammatory responses in the skin of rabbits. "
03/01/2015 - "Our findings suggest that CV-3988 and Ginkgolide B may be therapeutically useful in the treatment of CNV and inflammation."
|3.||Septic Shock (Toxic Shock Syndrome)
02/01/1995 - "These results suggest the effectiveness of CV-3988 in the treatment of endotoxic shock."
08/01/1995 - "Administration of either TCV-309 or CV-3988 alleviated the histologic lesions caused by endotoxic shock. "
08/01/1995 - "These results suggest that lung injury during endotoxic shock can be controlled by TCV-309 as by CV-3988."
07/01/1987 - "The results of the present study suggest that prostaglandin E2 and CV-3988 may have acted via a similar mechanism, possibly involving inhibition of a mediatory role of platelet-activating factor in endotoxic shock."
02/01/1995 - "The effect of CV-3988, a platelet activating factor antagonist, in the treatment of endotoxic shock was evaluated from the changes in plasma 6-keto-PGF1 alpha and thromboxane B2 concentrations. "
01/01/1992 - "In the present study, we evaluated the effect of the specific PAF antagonists CV-6209 and CV-3988 on accelerated nephrotoxic serum nephritis (NTN) in the rat. "
01/01/1992 - "Effects of the platelet-activating factor antagonists CV-6209 and CV-3988 on nephrotoxic serum nephritis in the rat."
|5.||Hypotension (Low Blood Pressure)
09/01/1989 - "Some of the cyclic antagonists showed more potent inhibitory activities than the open chain antagonist CV-3988 against platelet aggregation (rabbit platelet-rich plasma, IC50) and hypotension (rat, ID50) induced by C16-PAF: e.g. "
07/01/1987 - "At the dose tested, CV-3988 (10 mg/kg i.v.) also significantly reduced endotoxin-induced hypotension and gastric damage. "
01/01/1986 - "Hypotension induced by another endotoxin (Salmonella abortus equi) could also be attenuated by CV-3988. "
01/01/1986 - "In another series of animals which were pithed and vagotomized, hypotension, induced by endotoxin (6 mg/kg) (iv) could be attenuated by CV-3988. "
01/01/1986 - "Hypotension induced by PAF (3.0 micrograms/kg) (iv) was attenuated only by CV-3988 (10 mg/kg). "
|1.||Histamine (Histamine Dihydrochloride)
|4.||Silicon Dioxide (Sand)
|7.||Platelet Activating Factor
|10.||Serotonin (5 Hydroxytryptamine)
|2.||Surgical Instruments (Clip)