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triphenylethylene

Networked: 75 relevant articles (6 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jordan, V C: 2 articles (09/2014 - 12/2000)
2. Giustozzi, Giammario: 2 articles (03/2005 - 04/2002)
3. Marinucci, Lorella: 2 articles (03/2005 - 04/2002)
4. Balducci, Chiara: 2 articles (03/2005 - 04/2002)
5. Locci, Paola: 2 articles (03/2005 - 04/2002)
6. Lilli, Cinzia: 2 articles (03/2005 - 04/2002)
7. Cagini, Lucio: 2 articles (03/2005 - 04/2002)
8. Cabot, Myles C: 1 article (09/2015)
9. Morad, Samy A F: 1 article (09/2015)
10. Obiorah, I E: 1 article (09/2014)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Neoplasms (Cancer)
3. Carcinoma (Carcinomatosis)
12/01/1992 - "Antitumor effect of triphenylethylene derivative (TAT-59) against human breast carcinoma xenografts in nude mice."
12/01/1992 - "The antitumor activity of a newly synthesized triphenylethylene derivative [(E)-4-[1-[4-[2-(dimethylamino)ethoxy-phenyl]-2-(4-isopropyl)phenyl-1- butenyl] phenyl monophosphate] (TAT-59) was investigated against human breast carcinoma xenografts in nude mice with reference to the changes of hormone receptors. "
05/01/1994 - "The triphenylethylene drug tamoxifen is a hepatocarcinogen in rats, has genotoxic potential and may produce carcinoma of the endometrium in humans, while the structurally closely related toremifene has no carcinogenic or genotoxic potential. "
11/01/1995 - "1. This study has two specific aims: (a) to compare the antioestrogenic activity of two steroidal analogues of 17 beta-oestradiol, the 7 alpha-alkylamide, ICI 164,384 and the 7 alpha-alkylsulphinylamide, ICI 182,780, with that of the triphenylethylene-derived compound 4OH-tamoxifen on a pool of human breast cancer cell lines (HBCCL) with a range of hormonal responsiveness and acquired anti-oestrogen resistance and (b) to investigate the ability of such antioestrogens to modulate the potent breast carcinoma growth-stimulatory activity of the 'IGF-I system'. "
09/01/1997 - "The triphenylethylene antiestrogenic agents, tamoxifen (TX) and toremifene (TO), are currently being used for the therapy of estrogen dependent breast carcinomas and for some other estrogen receptor positive tumors. "
4. Glioma (Gliomas)
5. Body Weight (Weight, Body)

Related Drugs and Biologics

1. Toremifene (Fareston)
2. Tamoxifen
3. Estrogen Receptor Modulators (Antiestrogen)
4. Estrogens (Estrogen)
5. Protein Kinase C
6. Hormones
7. Estradiol (Estrace)
8. fulvestrant (Faslodex)
9. TAT 59
10. Insulin-Like Growth Factor I (IGF-1)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Nanospheres
3. Heterologous Transplantation (Xenotransplantation)
4. Radiotherapy
5. Ovariectomy (Oophorectomy)