HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

trimethyltin hydroxide

neurotoxic cpd

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organotin Compounds: 41
    - Trialkyltin Compounds: 1
      - Trimethyltin Compounds
        trimethyltin hydroxide: 4

Experts

1.	Lefebvre d'Hellencourt, Christian: 2 articles (02/2008 - 08/2003)
2.	Aoyama, Mineyoshi: 1 article (02/2008)
3.	Funk, Jason A: 1 article (02/2008)
4.	Harry, G Jean: 1 article (02/2008)
5.	McPherson, Christopher A: 1 article (02/2008)
6.	Bruccoleri, Alessandra: 1 article (08/2003)
7.	Jean Harry, G: 1 article (08/2003)

Related Diseases

1.	Body Weight (Weight, Body) 03/01/1987 - "Male C57B1/6N mice, 8-10 weeks old were given a single oral dose of 0, 1.0 or 3.0 mg/kg body weight of trimethyltin hydroxide (TMT). " 06/01/1995 - "mRNA levels for interleukin (IL)-1 alpha, IL-1 beta, IL-6 and tumor necrosis factor (TNF) alpha were measured in the hippocampus of adult male Long-Evans hooded rats following an acute injection of trimethyltin hydroxide (8 mg TMT/kg body weight). "
2.	Necrosis 08/15/2003 - "To examine their role in initiation of an acute hippocampal injury response, 21-day-old male CD-1 mice received an acute intraperitoneal (i.p.) injection of trimethyltin hydroxide (TMT; 2.0 mg/kg) to produce necrosis of dentate granule neurons, astrocyte, and microglia reactivity. "
3.	Neuroinflammatory Diseases 02/15/2008 - "To investigate the influence of IL-1R1 activation in the pathophysiology of a chemical-induced injury to the murine hippocampus, we examined the level and pattern of neuronal death and neuroinflammation in male weanling mice exposed to trimethyltin hydroxide (2.0 mg TMT/kg, i.p.). "

Related Drugs and Biologics

1.	Interleukin-1beta (Interleukin 1 beta)
2.	Interleukin-6 (Interleukin 6)
3.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4.	Messenger RNA (mRNA)
5.	Interleukins