|1.||Eisenhut, Michael: 4 articles (01/2014 - 12/2002)|
|2.||Mai, Antonello: 3 articles (09/2015 - 04/2010)|
|3.||Park, Kaapjoo: 3 articles (04/2014 - 12/2012)|
|4.||Haberkorn, Uwe: 3 articles (01/2014 - 12/2002)|
|5.||Mier, Walter: 3 articles (01/2014 - 12/2002)|
|6.||Friebe, Matthias: 3 articles (01/2014 - 12/2002)|
|7.||Mach, Robert H: 3 articles (01/2013 - 06/2006)|
|8.||Tu, Zhude: 3 articles (01/2013 - 06/2006)|
|9.||Xu, Jinbin: 3 articles (01/2013 - 06/2006)|
|10.||Little, Patrick J: 3 articles (09/2012 - 10/2008)|
01/01/1976 - "Metoclopramide, 4-amino-5-chloro-2-methoxy-N-(2-diethyl-aminoethyl) benzamide, is advocated for use in gastro-intestinal diagnostics, and in treating various types of vomiting and a variety of functional and organic gastro-intestinal disorders. "
02/11/1982 - "[A study of alizapride, a new benzamide, in nausea and emesis in internal medicine (author's transl)]."
11/15/2009 - "Levosulpiride is a substituted benzamide that is widely used for the management of dyspepsia and emesis. "
01/01/1992 - "This study shows that ondansetron is superior to a benzamide-corticosteroid combination in the control of acute cisplatin-induced emesis."
02/01/2005 - "If nausea and vomiting occurs during subsequent cycles of chemotherapy, prophylaxis with a single agent such as a substituted benzamide, a corticosteroid, or a phenothiazine should be administered. "
12/01/1985 - "Synthesis, toxicity, and therapeutic efficacy of 4-amino-N-(2'-aminophenyl)-benzamide: a new compound preferentially active in slowly growing tumors."
04/01/2010 - "Since then, a number of HDACi belonging to the short-chain fatty acid, hydroxamate, cyclic peptide or benzamide classes have been investigated in Phase II or III clinical trials (alone or in combination) for the treatment of many kinds of tumors. "
01/01/2012 - "Here, we propose a novel HDAC inhibitor, N-Hydroxy-4-(4-phenylbutyryl-amino) benzamide (HTPB), as a potential chemotherapeutic drug for solid tumors. "
12/01/2009 - "[Synthesis and anti-tumor activities of N-(aminopyridine) benzamide derivaties]."
06/01/2009 - "[Synthesis and anti-tumor activities of N-substituted benzamide derivatives]."
|3.||Schizophrenia (Dementia Praecox)
12/30/2013 - "Hence, the reduced amount of benzamide binding to the D2 receptors in the schizophrenia thalamus suggests that there is a reduced amount of D2Short receptors in this diseased region, and may possibly also mean fewer presynaptic terminals because that is where D2Short receptors mostly reside. "
01/01/1984 - "The unique properties of the substituted benzamide drugs might explain their clinical value in the treatment of schizophrenia and in the treatment of dyskinesias."
06/01/1986 - "In order to test this bipolar hypothesis two independent controlled studies were set up using the same new benzamide compound (amisulpride) at different doses in the opposite forms of schizophrenia. "
01/01/1985 - "An open study of remoxipride, a benzamide derivative, in schizophrenia."
12/30/2013 - "Schizophrenia thalamus imaging: low benzamide binding to dopamine D2 receptors suggests fewer D2Short receptors and fewer presynaptic terminals."
05/01/1992 - "2. The pyrrolidinyl benzamide (U-49524E) was found to be effective against the electroshock-induced seizures (ED50 = 35 mg kg-1, i.p.) whereas the benzamide with a piperidinyl moiety (U-49132E) was inactive (ED50 greater than 100 mg kg-1). "
09/01/2008 - "In the present study, we evaluate the effects of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], an orally bioavailable, potent, and selective KCNQ2/Q3 opener, in a broad range of rodent seizure models. "
07/01/2009 - "Finally, audiogenic seizures could be induced in wild-type mice by coadministering CGP 46381 and the mGluR5-positive allosteric modulator 3-cyano-N-(1,2 diphenyl-1H-pyrazol-5-yl) benzamide. "
05/01/1992 - "1. A pair of benzamide analogues containing a pyrrolidinyl or piperidinyl group was examined for their anticonvulsant activity against the electroshock-induced seizures in mice and the ability to block the voltage-gated Na channel in N1E-115 cells, in comparison with the prototype compound, U-54494A, (+/-)-cis-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]-ben zam ide , a potent anticonvulsant and a Na channel blocker. "
10/01/1987 - "[Effect of benzamide derivatives on convulsions induced by the toxic action of oxygen in rats]."
|5.||Neoplasm Metastasis (Metastasis)
01/01/2011 - "The efficacy of differing routes of administration of 18F-6-fluoro-N-[2-(diethylamino)ethyl] pyridine-3-carboxamide (18F-MEL050), a new benzamide-based PET radiotracer for imaging regional lymph node metastasis in melanoma, was assessed. "
07/01/2003 - "Wf-536, (+)-(R)-4-(1-Aminoethyl)-N-(4-pyridyl) benzamide monohydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models. "
01/17/2003 - "In the present study, we investigated the suppressive effect of a novel inhibitor of ROCK, Wf-536 [(+)-(R)-4-(1-Aminoethyl)-N-(4-pyridyl) benzamide monohydrochloride], on spontaneous tumor metastasis in vivo and analyzed its action on tumor cell motility and angiogenesis to clarify its action mechanism. "
01/01/2014 - "Moreover, benzamide derivatives radiolabeled with therapeutic radionuclide may offer a new strategy for the treatment of metastatic melanoma patients harboring melanin-positive metastases."
05/01/1998 - "We examined the anti-tumor effect of a novel benzoic acid derivative, TAC-101 (4-[3,5-bis(trimethylsilyl) benzamide] benzoic acid) on models with liver metastasis. "
|3.||Antipsychotic Agents (Antipsychotics)
|6.||Dopamine Receptors (Dopamine Receptor)
|7.||Poly Adenosine Diphosphate Ribose
|8.||Risperidone (Risperdal Consta)
|2.||Bone Marrow Transplantation (Transplantation, Bone Marrow)
|3.||Heterologous Transplantation (Xenotransplantation)
|5.||Drug Therapy (Chemotherapy)