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HOE 892
platelet aggregation inhibitor; structure given in first source
Also Known As:
HOE-892; S 79 2892 A; beta-thia-imino-prostacyclin; Butanoic acid, 4-((3,3a,4,5,6,6a-hexahydro-5-hydroxy-4-(3-hydroxy-1-octenyl)cyclopenta(b)pyrrol-2-yl)thio)-, methyl ester, (3aR-(3aalpha,4alpha(1E,3S*),5beta,6aalpha))-
Networked:
2
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Lipids: 114793
Fatty Acids: 27405
Unsaturated Fatty Acids: 8236
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins I: 108
Epoprostenol: 4670
HOE 892: 2
Biological Factors: 2472
Inflammation Mediators: 1113
Autacoids: 276
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins I: 108
Epoprostenol: 4670
HOE 892: 2
Related Diseases
1.
Necrosis
10/01/1984 - "
Both PGI2 and Hoe 892 were equally effective against gastric mucosal necrosis induced by absolute ethanol and this effect was observed both after i.g.
"
2.
Stomach Ulcer (Gastric Ulcer)
10/01/1984 - "
reduced dose-dependent gastric ulcer formation induced by acidified aspirin (ASA), Hoe 892 being somewhat less potent than PGI2.
"
3.
Renal Hypertension
03/01/1983 - "
Intravenous injection of Hoe 892 induced a dose dependent decrease of systemic BP in anesthetized rats (ED25 of 2.2 micrograms/kg) and in the rats with acute renal hypertension.
"
Related Drugs and Biologics
1.
Ethanol (Ethyl Alcohol)
2.
Aspirin (Acetylsalicylic Acid)
Related Therapies and Procedures
1.
Intravenous Injections