HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
methotrexate-gamma-aspartate
used in antibody targeted liposomes
Networked:
2
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Pteridines: 147
Pterins: 160
Aminopterin: 248
Methotrexate: 24010
methotrexate-gamma-aspartate: 2
Related Diseases
1.
Lymphoma (Lymphomas)
05/01/1984 - "
We report here the efficacy of targeted liposomes containing methotrexate-gamma-aspartate against two murine T-lymphomas, AKR/J SL2 and R1.1. Both large and small unilamellar vesicles conjugated to anti-Thy-1.1 antibody associated with AKR lymphoma cells in 10-fold greater amounts than nonconjugated liposomes or liposomes conjugated to a nonspecific antibody.
"
2.
Leukemia
07/01/1984 - "
Encapsulation of methotrexate-gamma-aspartate in antibody-conjugated liposomes increased its toxicity for K562 cells, a human leukemia cell line that expresses Fc receptors and human glycophorin A.
"
Related Drugs and Biologics
1.
Liposomes (Liposome)
2.
Unilamellar Liposomes
3.
Fc Receptors (Fc Receptor)
4.
Glycophorins (Glycophorin C)