|1.||Ohya, N: 3 articles (07/2001 - 01/2001)|
|2.||Nambu, Y: 3 articles (07/2001 - 01/2001)|
|3.||Sakuma, T: 3 articles (07/2001 - 01/2001)|
|4.||Toga, H: 3 articles (07/2001 - 01/2001)|
|5.||Osanai, K: 3 articles (07/2001 - 01/2001)|
|6.||Takahashi, K: 3 articles (07/2001 - 01/2001)|
|7.||Ishigaki, M: 2 articles (07/2001 - 01/2001)|
|8.||Tuchihara, C: 2 articles (07/2001 - 01/2001)|
|9.||Matthay, M A: 2 articles (07/2001 - 01/2001)|
|10.||Inoue, M: 2 articles (07/2001 - 02/2001)|
11/01/1985 - "The efficacy of denopamine, an orally active beta 1-adrenoceptor agonist, in improving cardiac failure was assessed in dog heart-lung preparations. "
11/01/1985 - "The results warrant clinical trials of denopamine in the treatment of cardiac failure."
12/01/1996 - "We studied the effect of the cardiotonic agent denopamine on the life span of cardiomyopathic hamsters (BIO 14.6 strain) in the heart failure period. "
05/01/1993 - "The short-term effects of denopamine, an orally available beta-stimulant, on exercise capacity were studied in patients with chronic heart failure. "
05/01/1993 - "Short-term effects of denopamine on anaerobic threshold and related parameters in patients with chronic heart failure: a double-blind crossover study."
03/01/1993 - "Efficacy of denopamine, a beta 1 adrenoceptor agonist, in preventing coronary artery spasm."
03/01/1993 - "These results suggest that 1) denopamine is a safe and effective medication for vasospastic angina; 2) beta 1 adrenoceptors may play an important role in the prevention of coronary artery spasm."
07/01/1991 - "Therefore the response to denopamine and the lack of response to prazosin in this patient suggests that not only the adrenergic alpha receptor but also the adrenergic beta-1 receptor plays an important role in the production of coronary spasm, at least in some patients."
|3.||Dyspnea (Shortness of Breath)
10/01/1989 - "After about 6 weeks' use of denopamine, her mean pulmonary arterial pressure decreased to 15 mmHg, PO2 increased from 43 to 62 mmHg and dyspnea improved. "
10/01/1989 - "Denopamine, beta-adrenergic agonist, decreased her high pulmonary arterial pressure and improved dyspnea on exercise after long term use. "
01/01/2002 - "To date, in Japan nine cases have been recognized of patients with vasospastic angina pectoris whose symptoms were relieved by taking denopamine, including one case in which the author has had personal experience. "
01/01/2002 - "It would therefore be worthwhile to determine whether denopamine is able to relieve vasospastic angina pectoris in many more cases."
|5.||Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
02/01/1992 - "In 9 patients with dilated cardiomyopathy, the effects of beta 1-agonist were tested at the beginning of therapy (30 mg/day denopamine) and 6 months later. "
03/01/1987 - "In 18 patients with dilated cardiomyopathy (DCM), the effects of a new cardiotonic agent, TA-064, given in both consecutive and intermittent (3 days on, 11 days off) oral doses were studied for 3 months by echocardiography and endomyocardial biopsy. "
08/01/1985 - "We analyzed computer-assisted alterations of pressure-volume relationships serially and of indirect myocardial oxygen consumption (MVO2) estimations on line during TA-064 influence in 16 patients with congestive cardiomyopathy: left ventricular function was moderately decreased in seven patients (group A) and drastically decreased in nine (group B). "
12/01/1984 - "We analyzed computer-assisted alterations of pressure-volume relations serially and of MVO2 online (Bretschneider) during TA-064 influence in 16 patients with congestive cardiomyopathy: LV-function of 7 patients was only moderately decreased (group A) and in 9 patients massively (group B). "
05/01/1993 - "Three patients had ischemic heart disease, 13 had dilated cardiomyopathy, and three had valvular disease; 16 patients were in New York Heart Association class II, and three patients were in New York Heart Association class III. Symptom-limited exercise testing (ramp protocol) on a bicycle ergometer with gas exchange analysis was conducted 1 hour after oral administration of either 20 mg denopamine or placebo. "
|1.||Adrenergic Receptors (Adrenergic Receptor)
|2.||Adrenergic beta-Agonists (beta-Adrenergic Agonists)
|4.||Adrenergic Agonists (Adrenergic Receptor Agonist)
|8.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|1.||Renal Dialysis (Hemodialysis)