COMP protocol

chemotherapy protocol consisting of above 4 cpds; see also record for COMP-1 in which prednisone is replaced by procarbazine; do not confuse with MCOP protocol

Also Known As:

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Therapy Context: Research Results

Experts

1.	Al-Tonbary, Youssef: 1 article (04/2010)
2.	El-Ashry, Rasha A: 1 article (04/2010)
3.	Fouda, Ashraf: 1 article (04/2010)
4.	Salama, Emad: 1 article (04/2010)
5.	Sarhan, Mohamed M: 1 article (04/2010)
6.	Sedki, Mohamed: 1 article (04/2010)

Related Diseases

1.	Glioma (Gliomas) 01/01/1979 - "Combination chemotherapy (COMP protocol) and radiotherapy of anaplastic supratentorial gliomas." 06/10/1983 - "A controlled study of 226 age-matched patients with histologically proven grade 3 and 4 supratentorial gliomas with maximum feasible tumour resection, postoperative Karnofsky performance over 50 and minimum survival of 8 weeks compares the results of supportive care (45 cases), high-dose irradiation of 40 to 66 Gy (59 cases), COMP protocol (CCNU, procarbazine, vincristine, methotrexate, prednisone in 15 day cycles-42 cases) and simultaneous irradiation and COMP chemotherapy (80 cases including 30 survivors). "
2.	Chemical and Drug Induced Liver Injury 04/01/2010 - "Toxic hepatitis or liver cell failure was recorded in 5% of patients treated with the COMP protocol. "

Related Drugs and Biologics

1.	Vincristine (Oncovin)
2.	Procarbazine (Matulane)
3.	Prednisone (Sone)
4.	Methotrexate (Mexate)
5.	Lomustine (CCNU)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Radiotherapy
3.	Combination Drug Therapy (Combination Chemotherapy)