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phosphatidylinositol 4-phosphate

Also Known As:
1-(3-sn-phosphatidylinositol)-L-myoinositol-4-phosphate; PI4P compound; PtdINS4P; phosphatidylinositol 4-monophosphate
Networked: 35 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Wedegaertner, P B: 1 article (03/2015)
2. Smrcka, A V: 1 article (03/2015)
3. Trembley, M: 1 article (03/2015)
4. deRubio, R G: 1 article (03/2015)
5. Malik, S: 1 article (03/2015)
6. Irannejad, R: 1 article (03/2015)
7. Han, Qingxia: 1 article (11/2014)
8. Ambrose, Rebecca L: 1 article (11/2014)
9. Sanchez-Felipe, Lorena: 1 article (11/2014)
10. Konan, Kouacou V: 1 article (11/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Anoxia (Hypoxia)
03/01/1991 - "The dynamic of the phosphatidylinositol (PI), the phosphatidylinositol 4-phosphate (PIP) and the phosphatidylinositol-4,5-diphosphate (PIP2) contents were studied in the correlation with the neuronal spike activity in cat brain cortex under acute oxygen deficiency caused by cessation of artificial ventilation for 1, 2.5 and 5 min. It was shown that the 1-min anoxia produced the depression of both PIP and PIP2 contents. "
12/01/1988 - "The hypoxia-induced decrease in JF was associated with four- to fivefold increase in phosphatidylinositol 4-phosphate (PIP) total pool size, suggesting PIP kinase was inhibited and rate limiting. "
11/01/1994 - "During glucose-free hypoxia, phosphatidylinositol 4,5-bisphosphate, the substrate for phospholipase C, but not phosphatidylinositol or phosphatidylinositol 4-monophosphate was seen to decline to 59% of normoxic values which was independent of activation of phospholipase C by agonists. "
09/01/1989 - "ADP inhibited [32P]PtdIns4P formation competitively with respect to ATP, the Ki being 0.4 mM. The data indicate that ADP is a poor competitive inhibitor of PtdIns kinase at the concentrations which are believed to be present intracellularly normally or which may be attained during mild hypoxia provided ATP levels are maintained in the millimolar range. "
09/06/1988 - "The cerebral concentrations of phosphatidylinositol (PI), phosphatidylinositol 4-phosphate (PIP), phosphatidylinositol 4,5-bisphosphate (PIP2), phosphatidic acid (PA), triacylglycerol (TAG) and free fatty acids (FFA), as well as cerebral metabolites, were measured in rats subjected to 10 min of hypoxia and subsequent recovery of 7 or 30 min duration. "
4. Infection
5. Ischemia

Related Drugs and Biologics

1. Phosphatidylinositols (Phosphatidylinositol)
2. Phosphatidic Acids (Phosphatidic Acid)
3. Nonesterified Fatty Acids (NEFA)
4. Triglycerides (Triacylglycerol)
5. Phosphotransferases (Kinase)
6. Type C Phospholipases
7. 1-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)
8. wortmannin
9. Unilamellar Liposomes
10. Profilins (Profilin)