1,10-phenanthroline-5,6-dione
has antineoplastic, intercalating, and trypanocidal activities; structure given in first source
Also Known As:
1,10-PAD; phen-dione
Networked: 5
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
| 1. | Devereux, Michael:
2 articles
(01/2016 - 12/2006)
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| 2. | McCann, Malachy:
2 articles
(01/2016 - 12/2006)
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| 3. | Deb, Jolly:
1 article
(08/2020)
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| 4. | Ghosh, Ivy:
1 article
(08/2020)
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| 5. | Jana, Siddhartha Sankar:
1 article
(08/2020)
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| 6. | Lakshman, Triloke Ranjan:
1 article
(08/2020)
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| 7. | Paine, Tapan Kanti:
1 article
(08/2020)
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| 8. | Branquinha, Marta H:
1 article
(01/2016)
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| 9. | Galdino, Anna Clara M:
1 article
(01/2016)
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| 10. | Kellett, Andrew:
1 article
(01/2016)
|
Related Diseases
| 1. | Neoplasms (Cancer)
08/15/2013
- " An analog of 9,10-PQ in which the biaryl unit had been deleted displayed a reduced ability to induce tumor cell apoptosis, while the analogs 1,10-phenanthroline-5,6-dione (9) and pyrene-4,5-dione (10), which also had modified biaryl units, exhibited increased tumor cell apoptotic activity. " 12/01/2006
- " The anti-cancer chemotherapeutic potential of 1,10-phenanthroline-5,6-dione (phendione), [Cu(phendione)(3)](ClO(4))(2).4H(2)O and [Ag(phendione)(2)]ClO(4) were determined using four human cells lines, i.e. " 01/01/2013
- " Tumor cell death was evaluated by fluorescence microscopy and flow cytometry for the Sn(IV) compound and also for a Co(II) compound bearing 1,10-phenanthroline-5,6-dione as ligand. " 08/18/2020
- " Two zinc(ii)-NSAID complexes [(phendione)ZnII(NPR)2(H2O)2] (1) and [(phendione)ZnII(MFN)2] (2) (HNPR = naproxen and HMFN = mefenamic acid) of 1,10-phenanthroline-5,6-dione (phendione) were isolated and characterized to evaluate their potential as anti-cancer agents. "
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| 2. | Infections
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