procolipase

07/01/2005 - "Enterostatin resulted in a slight but significant reduction of HF intake and body weight. "
07/01/2005 - "This study investigated the chronic effect of enterostatin on body weight and some of the associated changes in postprandial metabolism. "
04/01/2006 - "Chronic treatment of rats with enterostatin decreases body weight and body fat. "
03/01/2002 - "We conclude that, in addition to its critical role in fat digestion, procolipase has essential functions in postnatal development and in regulating body weight set point."
03/01/2002 - "Decreased postnatal survival and altered body weight regulation in procolipase-deficient mice."

03/01/1999 - "The results of these studies show hyperenterostatinemia in obesity and a diminution in enterostatin secretion after satiety."
01/01/2009 - "Procolipase gene: no association with early-onset obesity or fat intake."
07/01/1997 - "Humans with obesity also exhibit a lower secretion of pancreatic procolipase after a test meal, compared with persons of normal weight."
12/01/1993 - "The ability of enterostatin to inhibit high-fat food intake and decrease insulin secretion may be important for the prevention of obesity and type II diabetes, conditions linked through hyperinsulinemia."
03/01/1999 - "Although enterostatin-like immunoreactivities exist in blood, brain, and gut, and exogenous enterostatins decrease fat appetite and insulin secretion in rats, the roles of these peptides in human obesity remain to be examined. "

10/01/2009 - "Microarray studies of the genomic response of both a human hepatoma cell line (HepG2 cells) and a mouse hypothalamic cell line (GT1-7 cells) to enterostatin suggested that it might regulate protein trafficking. "
06/01/2008 - "To further understand this response, we tested enterostatin's effect in a human hepatoma cell line (HepG2 cells) that was subjected to glucose deprivation, a condition known to induce angiogenesis in other tumor cell lines. "

10/01/2009 - "As Scamp2 is involved in glucose uptake in mouse Beta-TC6 insulinoma cells we tested enterostatin's effect in Beta-TC6 cells. "
06/01/2002 - "In insulinoma cells (INS-1) enterostatin was found to target F1F0-ATP synthase, causing an inhibition of ATP production, an increased thermogenesis and increased oxygen consumption. "

01/01/1996 - "It is concluded that an energy-restricted regimen leading to lower plasma insulin, triglyceride, and low-density lipoprotein cholesterol levels did not significantly affect the plasma enterostatin concentration in overweight subjects. "