HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
brodimoprim
inhibits dihydrofolate reductase
Also Known As:
2,4-diamino-5-(4-bromo-3,5-dimethoxybenzyl)pyrimidine; Ro 10-5970; Ro-10-5970
Networked:
29
relevant articles (
8
outcomes,
9
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Trimethoprim: 2082
brodimoprim: 29
Related Diseases
1.
Sinusitis
09/01/1991 - "
The results indicate that brodimoprim is safe and effective in the treatment of acute sinusitis in adults.
"
07/01/1994 - "
These results suggest that once-daily treatment with brodimoprim represents safe and effective therapy for adults with acute bacterial sinusitis.
"
10/01/1994 - "
Brodimoprim was shown to be effective in the treatment of acute sinusitis in adults, its efficacy being equal to that of doxycycline.
"
10/01/1994 - "
Therapeutic efficacy and tolerability of brodimoprim in comparison with doxycycline in acute sinusitis in adults.
"
07/01/1994 - "
Controlled study of brodimoprim and cephalexin in the treatment of patients with acute sinusitis in general practice.
"
2.
Respiratory Tract Infections (Respiratory Tract Infection)
12/01/1993 - "
The aim of the present study was to investigate the efficacy and tolerability of brodimoprim (10 mg/kg on the first day, 5 mg/kg/die onward) in the treatment of upper respiratory tract infections in children (age range: 2-14 years).
"
12/01/1993 - "
Respiratory infections in children: when is brodimoprim indicated?
"
12/01/1993 - "
Brodimoprim was studied in the treatment of acute respiratory tract infections in hospitalized, basically healthy, military conscripts.
"
12/01/1993 - "
Brodimoprim in acute respiratory tract infections.
"
12/01/1993 - "
Efficacy and tolerability of brodimoprim in respiratory tract infections.
"
3.
Infections
01/01/1985 - "
Considering the minimal inhibitory concentrations of potential target organisms and the slow elimination, the results suggest that brodimoprim may be useful in the treatment of infections, and that dosage once a day may be sufficient.
"
12/01/1993 - "
Efficacy and tolerability of brodimoprim in pediatric infections.
"
11/01/1982 - "
The use of RO 10-5970 in osseous infections is appealing because oral administration is possible; therefore, clinical trials appear warranted.
"
4.
Otitis Media with Effusion
12/01/1993 - "
Brodimoprim concentrations in bronchial mucosa, bronchial secretions and middle ear effusions.
"
12/01/1993 - "
The aim of this study was to investigate the penetration of brodimoprim into bronchial mucosa, bronchial secretion and middle ear effusion, in order to evaluate the efficacy of the antibiotic in respiratory tract infections.
"
5.
Hearing Loss (Hearing Impairment)
12/01/1993 - "
Brodimoprim resulted more efficacious in the reduction of symptoms, especially hypoacusis and tinnitus (p < 0.05 between treatments); tympanometry showed a higher number of normalizations in the brodimoprim group, without significant differences between treatments.
"
12/01/1993 - "
Brodimoprim resulted more effective in the reduction of hypoacusis and tinnitus; other symptoms demonstrated higher percentage reductions in the group under brodimoprim therapy.
"
Related Drugs and Biologics
1.
Anti-Bacterial Agents (Antibiotics)
2.
Doxycycline (Periostat)
3.
Norfloxacin
4.
Erythromycin (Erycette)
5.
Amoxicillin (Wymox)
6.
Cephalexin (Cefalexin)
7.
dihydrofolate
8.
Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
9.
Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)
10.
Tablets
Related Therapies and Procedures
1.
Therapeutics
2.
Oral Administration
3.
Drug Therapy (Chemotherapy)