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mycotrienol I

from Streptomyces rishiriensis T-23; structure given in first source

Also Known As:

Ansatrienol A

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - mycotrienol I: 1
  - Polyketides: 231
    - Macrolides: 4391
      - mycotrienol I: 1
- Quinones: 434
  - mycotrienol I: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - mycotrienol I: 1

Related Diseases

1.

Neoplasms (Cancer)

10/01/1983 - "An amphotericin B-resistant clone (AMBR-1) derived from cultured Chinese hamster V79 cells was cross-resistant to mycotrienins I and II, but not to mycotrienol I or II. These four ansamycin antibiotics were found to potentiate significantly the action of some anti-cancer agents including 5-fluorouracil, cis-diamminedichloroplatinum, bleomycin, mitomycin C and 6-mercaptopurine against cultured V79 cells. "

Related Drugs and Biologics

1.	Rifabutin (Ansamycin)
2.	Mitomycin (Mitomycin-C)
3.	Mercaptopurine (6 Mercaptopurine)
4.	Fluorouracil (Carac)
5.	Cisplatin (Platino)
6.	Bleomycin (Blenoxane)
7.	Anti-Bacterial Agents (Antibiotics)
8.	Amphotericin B (Amphotericin)