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oroselol

from roots of Heracleum sphondylium L.

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        oroselol: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        oroselol: 2

Experts

1.	Liu, Rui: 1 article (02/2022)
2.	Meng, Fanli: 1 article (02/2022)
3.	Su, Zhejun: 1 article (02/2022)
4.	Wang, Yangyang: 1 article (02/2022)
5.	Agrawal, Veena: 1 article (01/2017)
6.	Chopra, Madhu: 1 article (01/2017)
7.	Kapoor, Himanshi: 1 article (01/2017)
8.	Mahapatra, Sushil Chandra: 1 article (01/2017)
9.	Yadav, Nalini: 1 article (01/2017)

Related Diseases

1.	Mouth Neoplasms (Oral Cancer) 02/28/2022 - "Results showed that oroselol could potentially inhibit viability of oral cancer SSC-4 cells in time- and dose-reliant fashion. " 02/28/2022 - "Therefore, oroselol may prove to be a lead molecule in oral cancer chemotherapy provided further in vivo and toxicological studies are performed on it." 02/28/2022 - "Antiproliferative activity of an angular furanocoumarin-oroselol in human oral cancer cells is mediated via autophagy induction, inhibition of cell migration, invasion, and downregulation of PI3K/AKT signalling pathway."
2.	B-Cell Lymphoma (Lymphoma, B Cell) 01/01/2017 - "In silico docking of NJRE marker compounds: oroselol, jatamansinol, nardostachysin, jatamansinone and nardosinone have revealed their synergistic and multi-targeted interactions with Vestigial endothelial growth factor receptor 2 (VEGFR2), Cyclin dependent kinase 2 (CDK2), B-cell lymphoma 2 (BCL2) and Epidermal growth factor receptor (EGFR). "
3.	Neoplasms (Cancer) 02/28/2022 - "Cancer cell migration and invasion was potentially supressed by oroselol cell treatment. "

Related Drugs and Biologics

1.	ErbB Receptors (EGF Receptor)
2.	Cyclin-Dependent Kinase 2
3.	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)
4.	Furocoumarins (Furanocoumarins)
5.	nardostachysin
6.	nardosinone

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)