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13,14-dihydro-15-ketoprostaglandin E1

pulmonary metabolite of PGE1 in dogs; RN given refers to (11alpha)-isomer

Also Known As:

13,14-dihydro-15-keto-PGE1; 15-keto-13,14-dihydro-PGE1

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Alprostadil: 3107
        13,14-dihydro-15-ketoprostaglandin E1: 2
    - Monounsaturated Fatty Acids: 676
      - Alprostadil: 3107
        13,14-dihydro-15-ketoprostaglandin E1: 2
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Alprostadil: 3107
        13,14-dihydro-15-ketoprostaglandin E1: 2

Related Diseases

1.	Atopic Dermatitis (Atopic Eczema) 03/01/1997 - "We therefore measured plasma concentrations of 15-keto-13,14-dihydro-PGE1, which reflects endogenous PGE1 release, by gas chromatography-mass spectrometry in 31 patients with atopic dermatitis (aged 18-41 years, median 26 years) and in 31 healthy, age- and sex-matched control subjects. "
2.	Peripheral Arterial Occlusive Disease 1 03/01/1991 - "Since 13,14-dihydro-PGE1, in contrast to its precursors 15-keto-PGE1 and 15-keto-13,14-dihydro-PGE1, is biologically active, its formation could contribute to the beneficial effects of PGE1 administered intravenously in patients with peripheral arterial occlusive disease."

Related Drugs and Biologics

1.	Alprostadil (Muse)
2.	13,14-dihydroprostaglandin E1