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leucyl-leucyl-leucine

RN given refers to (L-Leu-L-Leu-L-Leu)-isomer

Also Known As:

Leu-Leu-Leu; trileucine

Networked: 10 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - leucyl-leucyl-leucine: 10

Experts

1.	Hu, Yu-Kun: 1 article (04/2014)
2.	Hu, Yuan-Yuan: 1 article (04/2014)
3.	Niu, Yu-Ming: 1 article (04/2014)
4.	Shen, Ming: 1 article (04/2014)
5.	Wu, Ming-Yue: 1 article (04/2014)
6.	Xie, Long-Chuan: 1 article (04/2014)
7.	Xu, Xiao-Ming: 1 article (04/2014)
8.	He, Yue-Dong: 1 article (11/2012)
9.	Huang, Juan: 1 article (11/2012)
10.	Li, Dan-Qing: 1 article (11/2012)

Related Diseases

1.	Neoplasms (Cancer) 11/01/2012 - "To study the anti-cancer activities of Z-Leu-Leu-Leu-cho (MG132) against human endometrial carcinoma HEC-1B and Ishikawa cells and the potential of MG132 in human endometrial cancer therapy. " 10/19/2010 - "Introduction of a trileucine endosome escape unit resulted in significantly increased AON delivery to tumor cells, inhibition of laminin-411 synthesis in vitro and in vivo, specific accumulation in brain tumors, and suppression of intracranial glioma growth compared with pH-independent leucine ester. "
2.	Endometrial Neoplasms (Endometrial Cancer) 11/01/2012 - "To study the anti-cancer activities of Z-Leu-Leu-Leu-cho (MG132) against human endometrial carcinoma HEC-1B and Ishikawa cells and the potential of MG132 in human endometrial cancer therapy. "
3.	Retinoblastoma (Glioblastoma, Retinal) 11/01/1999 - "This study deals with the apoptotic effect exerted on human retinoblastoma Y79 cells by both sodium butyrate and an inhibitor of 26S proteasome [z-Leu-Leu-Leu-CHO (MG132)] and their synergistic effect. "
4.	Neuroblastoma 01/15/2005 - "In the present study, a human neuroblastoma cell line expressing the C-terminal 100 residues of APP (SH-SY5Y-SPA4CT) was used to determine the effect of proteasome inhibition, by lactacystin and Bz-LLL-COCHO (benzoyl-Leu-Leu-Leu-glyoxal), on APP processing at the gamma-secretase site. "
5.	Leukemia 10/01/2004 - "This study was designed to investigate the molecular mechanism of apoptosis and G(2)/M arrest in leukemia cell line HL-60 induced by proteasome inhibitor MG132 (Z-Leu-Leu-Leu-CHO). "

Related Drugs and Biologics

1.	benzyloxycarbonylleucyl-leucyl-leucine aldehyde
2.	Proteasome Endopeptidase Complex (Proteasome)
3.	Proteasome Inhibitors
4.	Amyloid Precursor Protein Secretases (beta-Secretase)
5.	Butyric Acid (Butanoic Acid)
6.	Human Growth Hormone (Saizen)
7.	Proteins (Proteins, Gene)
8.	Peptides (Polypeptides)
9.	Netilmicin (Netromycin)
10.	Glyoxal (Ethanedial)

Related Therapies and Procedures

1.	Therapeutics