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2-amino-4-nitrophenol

Also Known As:

2-amino-p-nitrophenol

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Nitrophenols: 18
        2-amino-4-nitrophenol: 1
- Nitro Compounds: 66
  - Nitrophenols: 18
    - 2-amino-4-nitrophenol: 1

Related Diseases

1.	Carcinogenesis 06/01/1988 - "2-Amino-4-nitrophenol was nominated by the National Cancer Institute for toxicology and carcinogenesis studies because of widespread human exposure associated with its manufacture and use. " 06/01/1988 - "NTP Toxicology and Carcinogenesis Studies of 2-Amino-4-Nitrophenol (CAS No. 99-57-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)." 06/01/1988 - "Toxicology and carcinogenesis studies were conducted by administering 2-amino-4-nitrophenol (98% pure) in corn oil by gavage, 5 days per week, to groups of F344/N rats and B6C3F1 mice of each sex in 15-day, 13-week, and 2-year studies. "
2.	Adenoma (Adenomas) 06/01/1988 - "Conclusions: Under the conditions of these 2-year gavage studies, there was some evidence of carcinogenic activity of 2-amino-4-nitrophenol for male F344/N rats, as shown by increased incidences of renal cortical (tubular cell) adenomas. "
3.	Neoplasms (Cancer) 06/01/1988 - "Hemangiomas or hemangiosarcomas (combined) occurred in male mice that received 2-amino-4-nitrophenol (0/50; 1/50; 5/50); each tumor was present at a different site. "
4.	Lymphoma (Lymphomas) 06/01/1988 - "2-Amino-4-nitrophenol was mutagenic in the mouse lymphoma L5178Y/TK± assay without metabolic activation. "
5.	Hyperplasia 06/01/1988 - "The incidences of renal tubular cell hyperplasia were also increased in male rats exposed to 2-amino-4-nitrophenol. "

Related Drugs and Biologics

1.	Corn Oil (Oil, Corn)