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fluoresceinated methotrexate (FMTX)

inhibits tetrahydrofolate dehydrogenase; fluorescent dihydrofolate reductase probe for studies of methotrexate resistance; structure given in first source
Also Known As:
FMTX; PT 430; F-MTX; MTX-F; N(alpha)-(4-amino-4-deoxy-N(10)--methylpteroyl-N(epsilon)-4'-fluoresceinthiocarbamoyl)-L-lysine trihydrate; PT-430; PT430 cpd; gamma-fluoromethotrexate
Networked: 8 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Koutcher, Jason A: 2 articles (02/2005 - 10/2003)
2. Spees, William M: 2 articles (02/2005 - 10/2003)
3. Yang, Guangli: 2 articles (02/2005 - 10/2003)
4. Gade, Terence P F: 1 article (02/2005)
5. Tong, William P: 1 article (02/2005)
6. Bornmann, William G: 1 article (02/2005)
7. Gorlick, Richard: 1 article (02/2005)
8. Veach, Darren: 1 article (10/2003)
9. Bornmann, William: 1 article (10/2003)
10. Rubio, Maria Belen: 1 article (10/2003)

Related Diseases

1. Nephritis
2. Neoplasms (Cancer)
3. Leukemia P388
4. Proteinuria
5. Pain (Aches)

Related Drugs and Biologics

1. fluoresceinated methotrexate (FMTX)
2. Methotrexate (Mexate)
3. Glutamates (Glutamate, Potassium)
4. tebufenozide (Mimic)
5. Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)
6. Fluorouracil (Carac)
7. Antibodies

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)