prednylidene (Pred)

12/01/2021 - "Treatments with both DEX and PRED were associated with improvement in asthma status assessment scores, and there was no significant difference between the groups. "
01/01/2021 - "Physical training improved FVC(%pred) significantly in children with asthma. "
08/04/2022 - "A tendency towards higher diffusion capacity per liter lung volume was seen in participants with active asthma (KCO 100% predicted, 95% CI 97-104) compared with those in remission (KCO 94% pred., 95% CI 89-99) (P = 0.10). "
03/01/2022 - "We found that PA was effective in improving quality of life (QOL) [health related quality of life, (HRQoL) & Asthma Control Questionnaire, (ACQ): standard mean difference (SMD) =-0.80, 95% credible interval (CrI): -1.30 to -0.31; I2=86.9%, Pheterogeneity<0.001], pulmonary function (FEV1/pred) [weighted mean difference (MD) =0.47, 95% CrI: 0.03 to 0.90; I2=74.9%, Pheterogeneity<0.001], and maximal oxygen consumption (VO2max) (MD =1.18, 95% CrI: 0.87 to 1.48; I2=17.0%, Pheterogeneity=0.31). "
07/19/2022 - "IMT improved pulmonary function (FEV1%pred, FVC) and inspiratory muscle strength in subjects with stable asthma. "

03/01/2022 - "We included 43 studies (1282 people with COPD, mean age 66 years, 65% men, 49% FEV1%pred) and identified 13 outcomes, 46 outcome measures and 22 instruments. "
01/01/2022 - "Thirty patients with COPD completed the study protocol (57% males; mean age: 64 ± 7 years; mean FEV1: 45 ± 17%pred). "
01/01/2018 - "Included studies enrolled participants with both partially reversible and non-reversible COPD and baseline mean per cent predicted (%pred) forced expiratory volume in one second (FEV₁) of 43.4 to 49.6. "
01/01/2018 - "40 patients with COPD completed the study protocol (65% males; mean age: 62.8 ± 7.3 years; mean FEV1: 45.8 ± 17.5 %pred). "
01/01/2016 - "Fifty-one mild to moderate COPD patients (66% males; median age 70 y; mean FEV1 56% of pred.) were enrolled in the study. "

01/01/2014 - "After 4 months the study subjects had significantly reduced their body weight (-26.0±11.8 kg) and BMI (-8.9±3.8) associated with a significant improvement of lung function (absolute changes: vital capacity +5.5±7.5% pred., p<0.001; FEV1+9.8±8.3% pred., p<0.001, ITGV+16.4±16.0% pred., p<0.001, SR tot -17.4±41.5% pred., p<0.01). "
12/01/1996 - "For Junior Infantry Soldier Recruits, there was no significant change in body weight but a significant reduction in pred VO2max (-2.4%) and a trend towards increased isometric muscular strength. "
01/01/2021 - "As the body weight increased, a statistically significant decrease in the FEV1/FVC ratio was observed, amounting to 84.6 [79.3; 90.0], 79.4 [76.6; 82.2], 74.6 [71.7; 77.5], 70.2 [67.0; 73.4]%, respectively, p=0.003; as well as a decrease in MEF 25 (% pred.), which amounted, respectively, to 95.6 [76.1; 115.2], 81.7 [71.4; 92.0], 56.3 [45.7; 66.9], and 48.4 [36.7; 60.1]%, p=0.003. "
01/01/2019 - "All participants underwent a pulmonary function test (forced expiratory volume in first second/forced vital capacity, FEV1/FVC; percentage value of predicted FEV1, FEV1%pred), a respiratory muscle strength test (maximal inspiratory pressure, MIP; maximal expiratory pressure, MEP), and an isokinetic test of dominant upper limb after a 24-hr interval (peak torque, PT; PT/body weight, PT/BW; total work, TW; endurance ratio, ER). "
07/01/2015 - "Management of body weight is important in reducing the overall healthcare costs, especially for subjects with PreD or T2D."

10/01/2018 - "Parenchymal inflammation and fibrotic changes significantly were reduced by myrtle and M-pred. "
01/01/2017 - "The majority of asthmatic subjects with FeNO ≥70 ppb exhibited high E/I MF levels in all lung fields (excluding the trachea) and V50%pred <80%, suggesting inflammation throughout the airway. "
05/01/2016 - "E/I LF was significantly correlated with airway narrowing (forced expiratory volume in 1 second [FEV1.0]/forced vital capacity [FVC]%: r = -0.50, maximal expiratory flow at 50% [V50],%pred: r = -0.50) and peripheral airway inflammation (alveolar NO: r = 0.36, eosinophils in peripheral sputum: r = 0.41). "
01/01/2008 - "Tissue inflammation was significantly attenuated in PRED dogs. "
01/01/1984 - "PRED also diminished degeneration and inflammation. "

11/12/2022 - "A positive response to treatment, as well as preserved baseline VCmax (% pred.) and TLC (% pred.), predicted longer survival, while fibrosis in HRCT was related to a worse prognosis. "
01/01/2020 - "Transcriptomic analysis identified that combining Pred with dnMstn treatment affects gene expression profiles associated with inflammation, metabolism, and fibrosis. "
07/01/2011 - "However, compared with andrographolide group A and BLM group, the fibrosis at day 14, 28 was significantly reduced.(3) The concentration of TGF-β1, TNF-α in BALF of NS group was significantly lower than that of Pred group, BLM group, andrographolide group A, B, C at each time point(P<0.05). "
01/01/2017 - "In clinical studies, a raised DLNO/DLCO ratio (≥110% predicted versus a control group), plus a low DLNO and DLCO (<67% pred), predicts pulmonary vascular disease, while a low DLNO/DLCO ratio, with similarly reduced DLNO and DLCO, is associated with interstitial lung disease with fibrosis. "
11/05/2019 - "The developed PBPK drug-disease models have efficiently described rifampicin PK in tuberculosis and cirrhosis populations after administering single drug dose, as the ratio(Obs/pred) for all the PK parameters were within a two-fold error range. "