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ascorbyl monostearate (ascorbyl stearate)

cpd prepared in microencapsulated form

Also Known As:

ascorbyl stearate; ascorbic acid stearate; ascorbylmonostearate

Networked: 10 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - Ascorbic Acid: 10913
        ascorbyl monostearate: 10
  - Acyclic Acids
    - Sugar Acids: 4
      - Ascorbic Acid: 10913
        ascorbyl monostearate: 10
Carbohydrates: 22023
- Sugar Acids: 4
  - Ascorbic Acid: 10913
    - ascorbyl monostearate: 10

Experts

1.	Naidu, K Akhilender: 5 articles (12/2016 - 01/2003)
2.	Coppola, Domenico: 3 articles (11/2007 - 01/2003)
3.	Naidu, Kamatham A: 3 articles (11/2007 - 01/2003)
4.	Kamatham, Akhilender Naidu: 2 articles (03/2019 - 02/2018)
5.	Mane, Shirish D: 2 articles (02/2018 - 12/2016)
6.	Cheng, Jin Q: 2 articles (11/2007 - 01/2006)
7.	Fang, Quan: 2 articles (11/2007 - 01/2006)
8.	Nicosia, Santo V: 2 articles (11/2007 - 01/2006)
9.	Mane, Shirish Dinkar: 1 article (03/2019)
10.	Sandur, Santosh K: 1 article (12/2016)

Related Diseases

1.	Sepsis (Septicemia) 06/10/2023 - "In this work, a potent hyaluronidase inhibitor (ascorbyl stearate (AS)) was successfully employed to design vancomycin-loaded solid lipid nanoparticles (VCM-AS-SLNs) with biomimetic and enzyme-responsive features, to enhance the antibacterial efficacy of vancomycin against bacterial-induced sepsis. "
2.	Glioblastoma (Glioblastoma Multiforme) 08/01/2001 - "Antiproliferative and apoptotic effect of ascorbyl stearate in human glioblastoma multiforme cells: modulation of insulin-like growth factor-I receptor (IGF-IR) expression." 08/01/2001 - "In this study, we present data on in vitro effect of ascorbyl stearate (Asc-S), a liphophilic derivative of ascorbic acid on cell proliferation, transformation, apoptosis and modulation of expression of insulin-like growth factor-I receptor (IGF-IR) in human glioblastoma multiforme (T98G) cells. "
3.	Ovarian Epithelial Carcinoma 01/01/2006 - "These studies indicate that the antiproliferative effect of ascorbyl stearate on ovarian epithelial cancer cells is associated with decreased PI3K/AKT activity, and point toward the PI3K/AKT signaling pathway as a target for this drug." 01/01/2006 - "The effect of ascorbyl stearate was studied in a panel of human ovarian epithelial cancer cells. "
4.	Neoplasms (Cancer) 12/01/2016 - "Ascorbyl Stearate Promotes Apoptosis Through Intrinsic Mitochondrial Pathway in HeLa Cancer Cells." 08/21/2003 - "Ascorbyl stearate was found to inhibit proliferation of human cancer cells by interfering with cell cycle progression, induced apoptosis by modulation of signal transduction pathways. " 01/01/2006 - "Ascorbyl stearate inhibits cell proliferation and tumor growth in human ovarian carcinoma cells by targeting the PI3K/AKT pathway."
5.	Pancreatic Neoplasms (Pancreatic Cancer) 01/01/2003 - "Here we studied the effects of ascorbyl stearate (Asc-S), a nontoxic, lipophilic derivative of ascorbic acid, on pancreatic cancer. " 01/01/2003 - "Antiproliferative and proapoptotic effect of ascorbyl stearate in human pancreatic cancer cells: association with decreased expression of insulin-like growth factor 1 receptor."

Related Drugs and Biologics

1.	Vancomycin
2.	Hyaluronoglucosaminidase (Hyaluronidase)
3.	Enzymes
4.	Lipid Nanoparticles
5.	Ascorbic Acid (Vitamin C)
6.	IGF Type 1 Receptor (IGF 1 Receptor)
7.	Sulfhydryl Compounds (Thiols)
8.	Palmitates
9.	Interferons
10.	Glutathione Transferase (Glutathione S-Transferase)