mexiprostil

RN given refers to (11alpha,13E,15R,16R)-isomer

Also Known As:

15 alpha,16(R),16-methyl-16-methoxy-PGE1; 15 alpha,16(R),16-methyl-16-methoxy-prostaglandin E1; 15 alpha,16-methyl-16-methoxy-PGE1; MDL 646; MDL-646; Prost-13-en-1-oic acid, 11,15-dihydroxy-16-methoxy-16-methyl-9-oxo-, (11alpha,13E,15R,16R)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Ulcer 08/01/1984 - "The supposed local activity coupled with the antisecretory effects and the good tolerability make it interesting to test MDL-646 as an anti-ulcer agent in man."
2.	Gastric Fistula 02/01/1983 - "In the conscious rat provided with gastric fistula MDL 646 (15 and 50 micrograms/kg) significantly inhibited spontaneous gastric secretion. " 02/01/1983 - "In the dog provided with gastric fistula and Heidenhain pouch, MDL 646 (25 micrograms/kg by intragastric administration) caused a remarkable inhibition of the histamine- and bethanechol-induced acid secretion, an effect which was more evident in the main stomach than on the Heidenhain pouch. "
3.	Fistula 08/01/1984 - "In conscious rats with chronic gastric fistulas, intragastrically administered (i.g.) MDL-646 affected both acid concentration and volume of unstimulated gastric secretion. "

Related Drugs and Biologics

1.	Acids
2.	Bethanechol (Duvoid)
3.	Histamine (Histamine Dihydrochloride)