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4,4'-dibenzamido-2,2'-stilbenedisulfonic acid

anion transport inhibitor; RN given refers to parent cpd
Also Known As:
4,4'-dibenzamido-2,2'-disulfonic stilbene; 4,4'-dibenzamido-2,2'-stilbenedisulfonic acid, disodium salt; DBDS
Networked: 133 relevant articles (6 outcomes, 24 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Faraone, Stephen V: 4 articles (01/2022 - 05/2006)
2. Hwang, Soonjo: 4 articles (01/2022 - 01/2017)
3. Miñambres, Eduardo: 4 articles (01/2022 - 06/2015)
4. Groat, Tahnee: 3 articles (12/2021 - 01/2020)
5. Malinoski, Darren J: 3 articles (12/2021 - 01/2020)
6. Niemann, Claus U: 3 articles (12/2021 - 01/2020)
7. Patel, Madhukar S: 3 articles (12/2021 - 01/2020)
8. Sally, Mitchell B: 3 articles (12/2021 - 01/2020)
9. Swanson, Elizabeth A: 3 articles (12/2021 - 01/2020)
10. Meffert, Harma: 3 articles (10/2021 - 01/2017)

Related Diseases

1. Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
2. Oppositional Defiant Disorder
3. Wounds and Injuries (Trauma)
10/01/2021 - "Conclusions: This study provides preliminary evidence that a serotonergic agent (fluoxetine) can reduce disruptive behavior and mood symptoms in youths with DBDs and trauma exposure and that this may be mediated by enhanced activation of top-down attention control and emotion regulation areas (inferior parietal lobule, insula cortex, and vmPFC)."
10/01/2021 - "Methods: There were three participant groups: (i) Youths with DBDs and trauma exposure who received fluoxetine treatment for 8 weeks (n = 11); (ii) A matched group of youths with DBDs and trauma exposure who received routine regular follow-up in an outpatient clinic (n = 10); and (iii) Typically developing youths (n = 18). "
10/01/2021 - "Objective: A preliminary investigation of the impact of a serotonergic agent (fluoxetine) on symptom profile and neural response in youths with disruptive behavior disorders (DBDs) and a history of trauma exposure. "
10/01/2021 - "Results: Youths with DBDs and trauma exposure who received fluoxetine treatment compared to the other two groups showed: (i) significant improvement in externalizing, oppositional defiant disorder, irritability, anxiety-depression, and trauma-related symptoms; (ii) as a function of fearful expression intensity, significantly decreased amygdala response and increased recruitment of regions implicated in top-down attention control (insula cortex, inferior parietal lobule, and postcentral gyrus) and emotional regulation (ventromedial prefrontal cortex [vmPFC]); and (iii) correlation between DBD/irritability symptom improvement and increased activation of top-down attention control areas (inferior parietal lobule, insula cortex, and postcentral gyrus) and an emotion regulation area (vmPFC). "
11/01/2021 - "Compared to livers and kidneys, many DBDs have lungs that are unsuitable for transplant, due to aspiration pneumonia, neurogenic pulmonary edema, trauma, and the effects of brain death on lung function. "
4. Anxiety Disorders (Anxiety Disorder)
5. Primary Graft Dysfunction

Related Drugs and Biologics

1. Fluoxetine (Prozac)
2. Risperidone (Risperdal Consta)
3. Solutions
4. Lipopolysaccharides
5. Formaldehyde (Formol)
6. Clozapine (Clozaril)
7. Olanzapine (Zyprexa)
8. Quetiapine Fumarate (Seroquel)
9. ziprasidone (Geodon)
10. serum P-component (CIt)

Related Therapies and Procedures

1. Critical Care (Surgical Intensive Care)
2. Contraception (Birth Control)
3. Liver Transplantation
4. Lung Transplantation
5. Heart Transplantation (Grafting, Heart)