|1.||Amin, Shantu: 2 articles (04/2004 - 07/2002)|
|2.||El-Bayoumy, Karam: 2 articles (04/2004 - 07/2002)|
|3.||Pittman, Brian: 2 articles (04/2004 - 07/2002)|
|4.||Desai, Dhimant: 2 articles (04/2004 - 07/2002)|
|5.||Boyiri, Telih: 2 articles (04/2004 - 07/2002)|
|6.||Lin, Jyh-Ming: 1 article (04/2004)|
|7.||Guttenplan, Joseph: 1 article (04/2004)|
|8.||Kosinska, Wieslawa: 1 article (04/2004)|
|9.||Khmelnitsky, Michael: 1 article (04/2004)|
|10.||Sharma, Arun K: 1 article (07/2002)|
04/01/2004 - "We determined the mutant fractions (MF) and mutational specificities in the cII gene in histologically confirmed normal, non-involved and tumor mammary tissues of female transgenic (Big Blue F344 x Sprague-Dawley)F1 rats treated with the environmental pollutant 6-nitrochrysene (6-NC). "
11/01/2000 - "The remarkable carcinogenic activity of 6-nitrochrysene (6-NC) in several animal models, and its environmental presence, suggest its potential importance with regard to human cancer development. "
11/01/1999 - "6-Nitrochrysene was the only test agent to produce a significant increase in the frequency of lung tumors. "
04/01/1999 - "While the liver tumor incidences for BaP, BaP trans-7,8-dihydrodiol, and the positive control 6-nitrochrysene (6-NC) were significantly higher than in the solvent control animals, all the other tested compounds exhibited no tumorigenicity. "
08/15/1993 - "Induction of mammary cancer by 6-nitrochrysene in female CD rats."
|2.||Hepatocellular Carcinoma (Hepatoma)
05/01/1985 - "A newborn mouse (BLU:Ha) lung adenoma bioassay demonstrated that 6-nitrochrysene was a highly potent tumorigen. "
05/01/1996 - "The environmental contaminant 6-nitrochrysene (6-NC) has been shown to induce adenomas and adenocarcinomas in the colons of rats. "
05/01/1988 - "Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay."
|1.||Mixed Function Oxygenases (Monooxygenases)
|7.||Cytochrome P-450 Enzyme System (Cytochrome P450)