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6-nitrochrysene

RN given refers to cpd with locant for nitro group in position 6

Networked: 16 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Phenanthrenes: 27
        Chrysenes
        6-nitrochrysene: 16
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Phenanthrenes: 27
    - Chrysenes
      - 6-nitrochrysene: 16

Experts

1.	Amin, Shantu: 2 articles (04/2004 - 07/2002)
2.	Boyiri, Telih: 2 articles (04/2004 - 07/2002)
3.	Desai, Dhimant: 2 articles (04/2004 - 07/2002)
4.	El-Bayoumy, Karam: 2 articles (04/2004 - 07/2002)
5.	Pittman, Brian: 2 articles (04/2004 - 07/2002)
6.	Guttenplan, Joseph: 1 article (04/2004)
7.	Khmelnitsky, Michael: 1 article (04/2004)
8.	Kosinska, Wieslawa: 1 article (04/2004)
9.	Lin, Jyh-Ming: 1 article (04/2004)
10.	Krzeminski, Jacek: 1 article (07/2002)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 08/15/1993 - "Induction of mammary cancer by 6-nitrochrysene in female CD rats." 07/01/2002 - "Therefore, one of the goals of this study was to determine the propensity of the environmental contaminant 6-nitrochrysene (6-NC) for inducing mammary cancer following its oral administration to female CD rats. "
2.	Hepatocellular Carcinoma (Hepatoma) 09/30/2000 - "Induction of cytochrome P450 1A1 in human hepatoma HepG2 cells by 6-nitrochrysene." 09/30/2000 - "The present study has determined the effects of 6-nitrochrysene (6-NC) on human cytochrome P450-dependent monooxygenases in human hepatoma HepG2 cells. "
3.	Neoplasms (Cancer) 02/25/2023 - "Meanwhile, 6-nitrochrysene had potential cancer risk (CR) for human in the coking site. " 11/01/2000 - "The remarkable carcinogenic activity of 6-nitrochrysene (6-NC) in several animal models, and its environmental presence, suggest its potential importance with regard to human cancer development. " 11/01/1999 - "6-Nitrochrysene was the only test agent to produce a significant increase in the frequency of lung tumors. " 02/01/1989 - "In the liver, trans-1,2-dihydro-1,2-dihydroxy-6-nitrochrysene was more active than 6-nitrochrysene based on the number of tumors per mouse. " 02/01/1989 - "Seven hundred nmol/mouse of 6-nitrochrysene induced significant incidences and multiplicities of lung tumors in both sexes; only males were susceptible to liver tumor induction. "
4.	Adenoma (Adenomas) 05/01/1985 - "A newborn mouse (BLU:Ha) lung adenoma bioassay demonstrated that 6-nitrochrysene was a highly potent tumorigen. " 05/01/1996 - "The environmental contaminant 6-nitrochrysene (6-NC) has been shown to induce adenomas and adenocarcinomas in the colons of rats. " 05/01/1988 - "Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay."
5.	Adenocarcinoma 05/01/1996 - "The environmental contaminant 6-nitrochrysene (6-NC) has been shown to induce adenomas and adenocarcinomas in the colons of rats. " 05/01/1985 - "70% of the 6-nitrochrysene treated mice had malignant lung tumors (adenocarcinomas). "

Related Drugs and Biologics

1.	Mixed Function Oxygenases (Monooxygenases)
2.	Cytochromes
3.	Benzo(a)pyrene
4.	pyrene
5.	Solvents
6.	Tetradecanoylphorbol Acetate
7.	Hydrocarbons
8.	Environmental Pollutants (Pollutants, Environmental)
9.	Cytochrome P-450 Enzyme System (Cytochrome P450)
10.	Carcinogens

Related Therapies and Procedures

1.	Oral Administration
2.	Aftercare (After-Treatment)
3.	Caloric Restriction