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nepitrin

Also Known As:

5,3',4'-trihydroxy-6-methoxyflavone; 6-methoxy-luteolin 7-glucoside; 6-methoxyluteolin 7-glucoside

Networked: 4 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        Luteolin: 1323
        nepitrin: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        Luteolin: 1323
        nepitrin: 4

Experts

1.	Alam, Aftab: 1 article (01/2021)
2.	Alrobaian, Majed M: 1 article (01/2021)
3.	Devi, Sushma: 1 article (01/2021)
4.	Rangra, Naresh Kumar: 1 article (01/2021)
5.	Rawat, Ravi: 1 article (01/2021)
6.	Singh, Akanksha: 1 article (01/2021)
7.	Singh, Randhir: 1 article (01/2021)
8.	Bang, Sunghee: 1 article (05/2018)
9.	Ha, Thi Kim Quy: 1 article (05/2018)
10.	Lee, Changyeol: 1 article (05/2018)

Related Diseases

1.	Dyslipidemias (Dyslipidemia) 01/01/2021 - "Outcomes of the preclinical results showed and proved that Nepitrin significantly improved dyslipidemia at an effective dose of 50 mg/kg as compared with HFD control and Simvastatin. "
2.	Inflammation (Inflammations) 07/01/1982 - "Nepitrin was found to possess significant anti-inflammatory activity in the exudative and proliferative phases of inflammation. " 07/01/1982 - "The anti-inflammatory efficacy of nepitrin (5,3',4'-trihydroxy-6-methoxy flavone), a flavonoid, was investigated in both acute and chronic models of inflammation in rats. "
3.	Amnesia (Dissociative Amnesia) 12/01/2017 - "In mice, nepitrin reversed the amnesia induced by scopolamine as indicated by a dose-dependent increase in spontaneous alternation performance in the Y-maze task (p <0.05 versus scopolamine) and increase in the discrimination index in the novel object recognition test (NORT) comparable to the standard drug donepezil 2mg/kg. Molecular docking studies were performed and the GlideScore of nepitrin was consistent with its experimental AChE inhibitory activities. "
4.	Atherosclerosis 01/01/2021 - "Various preclinical atherosclerosis parameters such as lipid levels, SGOT/SGPT, body weight, histology of aorta and heart were estimated and beneficial effect of Nepitrin in high-fat diet (HFD) induced atherosclerosis for six weeks were observed. "
5.	Memory Disorders (Memory Loss) 12/01/2017 - "Thus, nepitrin could provide a lead for the development of therapeutic agent useful in cognition and memory disorders such as Alzheimer's disease."

Related Drugs and Biologics

1.	Flavonoids
2.	Simvastatin (Zocor)
3.	Scopolamine (Hyoscine)
4.	Donepezil (Aricept)
5.	Lipids
6.	Aspartate Aminotransferases (Aspartate Transaminase)
7.	Alanine Transaminase (SGPT)
8.	6- methoxy- 4',5- dihydroxyflavone- 7- O- glucoside
9.	6-hydroxyluteolin