tamoxifen N-oxide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Breast Neoplasms (Breast Cancer) 08/01/2001 - "We demonstrate substantial variation among patient profiles, statistically significant differences in the amount of urinary tamoxifen N-oxide found in stages I, II, and III compared to stage IV breast cancer patients, and statistically significant differences in the amount of 3,4-dihydroxytamoxifen found in progressors compared to nonprogressors with metastatic (stage IV) cancer." 10/01/2005 - "Tamoxifen (TAM), used as the endocrine therapy of choice for breast cancer, undergoes metabolism primarily forming N-desmethyltamoxifen, 4-hydroxytamoxifen, alpha-hydroxytamoxifen, and tamoxifen-N-oxide (TNO). "
2.	Neoplasms (Cancer) 08/01/2001 - "We demonstrate substantial variation among patient profiles, statistically significant differences in the amount of urinary tamoxifen N-oxide found in stages I, II, and III compared to stage IV breast cancer patients, and statistically significant differences in the amount of 3,4-dihydroxytamoxifen found in progressors compared to nonprogressors with metastatic (stage IV) cancer."

1.	Tamoxifen
2.	3,4-dihydroxytamoxifen
3.	alpha-hydroxytamoxifen
4.	N-desmethyltamoxifen
5.	afimoxifene (hydroxytamoxifen)

1.	Therapeutics