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N-lauroylsphingosine
RN given refers to (R-(R*,S*-(E)))-isomer
Also Known As:
dodecyl sphingosine; laurylsphingosine; Dodecanamide, N-(2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl)-, (R-(R*,S*-(E)))-
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Ceramides: 4082
N-lauroylsphingosine: 2
Carbohydrates: 22023
Glycoconjugates: 1353
Glycolipids: 2799
Glycosphingolipids: 1659
Neutral Glycosphingolipids: 101
Ceramides: 4082
N-lauroylsphingosine: 2
Lipids: 114793
Glycolipids: 2799
Glycosphingolipids: 1659
Neutral Glycosphingolipids: 101
Ceramides: 4082
N-lauroylsphingosine: 2
Membrane Lipids: 1591
Sphingolipids: 3208
Glycosphingolipids: 1659
Neutral Glycosphingolipids: 101
Ceramides: 4082
N-lauroylsphingosine: 2
Related Diseases
1.
Farber Lipogranulomatosis
07/01/1989 - "
Leukocyte and plasma N-laurylsphingosine deacylase (ceramidase) in Farber disease.
"
08/01/1982 - "
Comparative kinetic studies of acid ceramidase activity with N-lauroylsphingosine and N-oleoylsphingosine demonstrated about 5 (2-12)-fold and 7 (4-17)-fold higher K(m) values in fibroblasts from patients with Farber disease as compared with normal controls.
"
08/01/1982 - "
N-Lauroylsphingosine, towards which acid ceramidase activity in control fibroblasts was about 10 times higher than that towards N-oleoylsphingosine, may serve as a better substrate for enzymic diagnosis of Farber disease as well as for further characterization of the catalytically defective acid ceramidase.
"
Related Drugs and Biologics
1.
Acid Ceramidase
2.
oleoylsphingosine
3.
Ceramidases