chitobiosyldiphosphodolichol beta-mannosyltransferase

adds mannose from GDP mannose to GlcNac-GlcNac-pyrophosphoryl-dolichol in beta-1,4 linkage; RefSeq NM_019109 (human)

Also Known As:

ALG1 protein, S cerevisiae; ALG1 protein, human; Asparagine-Linked Glycosylation 1 protein, S cerevisiae; DolPP-GlcNAc mannosyltransferase; ERC14 protein, S cerevisiae; GDP-Man - Dol-PP-GlcNAc2 mannosyltransferase; GDP-mannose-dolichyldiphosphate chitobiose mannosyltransferase; YBR110W protein, S cerevisiae; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase) protein, human; beta-1,4-mannosyltransferase; beta-1,4-mannosyltransferase, S cerevisiae; dolichol pathway enzyme III; dolichyl diP mannosyltransferase; dolichyl-diphosphate-N-acetylglucosaminyl2 mannosyltransferase

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Glycosyltransferases: 784
      - Hexosyltransferases
        Mannosyltransferases: 52
        chitobiosyldiphosphodolichol beta-mannosyltransferase: 1

Experts

1.	Hashimoto, Tasuku: 1 article (01/2018)
2.	Iwayama, Yoshimi: 1 article (01/2018)
3.	Jitoku, Daisuke: 1 article (01/2018)
4.	Kanahara, Nobuhisa: 1 article (01/2018)
5.	Kikuchi, Mitsuru: 1 article (01/2018)
6.	Kobayashi, Momoko: 1 article (01/2018)
7.	Kurumaji, Akeo: 1 article (01/2018)
8.	Nishikawa, Toru: 1 article (01/2018)
9.	Suzuki, Katsuaki: 1 article (01/2018)
10.	Toyota, Tomoko: 1 article (01/2018)

Related Diseases

Schizophrenia (Dementia Praecox)

01/01/2018 - "Association studies of WD repeat domain 3 and chitobiosyldiphosphodolichol beta-mannosyltransferase genes with schizophrenia in a Japanese population."
01/01/2018 - "Based upon the development-dependent onsets of these psychotomimetic effects, by using a DNA microarray technique, we identified the WD repeat domain 3 (WDR3) and chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) genes as novel candidates for schizophrenia-related molecules, whose mRNAs were up-regulated in the adult (postnatal week seven), but not in the infant (postnatal week one) rats by an indirect dopamine agonist, and phencyclidine, an antagonist of the NMDA receptor. "

Related Drugs and Biologics

1.	A-Form DNA (A-DNA)
2.	Dopamine Agonists (Dopamine Agonist)
3.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
4.	Phencyclidine (Angel Dust)