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3,3'-dithiobis(sulfosuccinimidyl propionate)

structure given in first source

Also Known As:

DTBSSP; DTSSP; 3-Pyrrolidinesulfonic acid, 1,1'-(dithiobis((1-oxo-3,1-propanediyl)oxy))bis(2,5-dioxo)

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Imides: 79
  - Succinimides: 11
    - 3,3'-dithiobis(sulfosuccinimidyl propionate): 6
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Succinimides: 11
        3,3'-dithiobis(sulfosuccinimidyl propionate): 6

Experts

1.	Jang, Jae-Hyung: 1 article (08/2020)
2.	Kang, Byunguk: 1 article (08/2020)
3.	Kim, Yunha: 1 article (08/2020)
4.	Oh, Seokmin: 1 article (08/2020)
5.	Yoo, Seungju: 1 article (08/2020)
6.	Cai, Amanda: 1 article (01/2020)
7.	Flynn, Nicholas: 1 article (01/2020)
8.	Ramsey, Joshua D: 1 article (01/2020)
9.	Seaberg, Joshua: 1 article (01/2020)
10.	Afanasyev, Boris V: 1 article (11/2016)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2020 - "As glutathione is upregulated in various cancers, DTSSP NPs could display destabilization within cancer cells. " 11/01/2016 - "In this report, we investigated intracellular redox induced drug release in cancerous cells and human mesenchymal stem cells (MSCs) as an example of healthy cells using redox-responsive microcapsules with covalently bonded anti-cancer drug (doxorubicin) via the amine-reactive cross-linker, 3,3'-dithiobis(sulfosuccinimidyl propionate) containing disulfide bond. "
2.	Hepatocellular Carcinoma (Hepatoma) 07/30/1985 - "We have investigated the structure of solubilized cytokeratins from Novikoff ascites hepatoma using the cleavable cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate) in the presence of 6 M urea to effect partial complex melting. " 06/01/1991 - "Haemopexin receptors from mouse hepatoma (Hepa) cells were affinity-labelled by cross-linking to haem-125I-haemopexin complexes using two homo-[disuccinimidyl suberate (DSS) and 3,3'-dithiobis(succinimidyl propionate) (DTSSP)] and one hetero-[sulphosuccinimidyl 4-(p-maleimidophenyl)butyrate (sulpho-SMPB)] bifunctional cross-linking agents. "
3.	Pancreatic Neoplasms (Pancreatic Cancer) 08/17/2020 - "At lower quantities of DTSSP, the AAV-DTSSP complexes were conjugated with aminated l-fucose molecules, whose levels are typically upregulated in pancreatic cancer cells, resulting in enhanced gene delivery efficiencies in pancreatic cancer cells. "
4.	Leukemia 11/03/1989 - "We observed that DTSSP is also a potent inhibitor of reduced folate/methotrexate transport in human CCRF-CEM leukemia cells. "
5.	Ascites 07/30/1985 - "We have investigated the structure of solubilized cytokeratins from Novikoff ascites hepatoma using the cleavable cross-linker 3,3'-dithiobis(sulfosuccinimidyl propionate) in the presence of 6 M urea to effect partial complex melting. "

Related Drugs and Biologics

1.	Urea (Carbamide)
2.	Methotrexate (Mexate)
3.	Glutathione (Reduced Glutathione)
4.	Fucose
5.	Folic Acid (Vitamin M)
6.	Doxorubicin (Adriamycin)
7.	Disulfides
8.	Capsules (Microcapsules)
9.	Amines
10.	hemopexin receptor