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histidylproline

Also Known As:

His-Pro

Networked: 17 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - histidylproline: 17

Experts

1.	Olsson, Anna-Karin: 2 articles (11/2009 - 08/2006)
2.	Thulin, Asa: 2 articles (11/2009 - 08/2006)
3.	Bhullar, Khushwant S: 1 article (01/2022)
4.	Fan, Hongbing: 1 article (01/2022)
5.	Wang, Zihan: 1 article (01/2022)
6.	Wu, Jianping: 1 article (01/2022)
7.	Kobayashi, Kanao: 1 article (07/2020)
8.	Muto, Masayuki: 1 article (07/2020)
9.	Shigematsu, Yoshinori: 1 article (07/2020)
10.	Bellezza, Ilaria: 1 article (01/2018)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2022 - "This study aims to investigate the protective effects of four chicken muscle-derived peptides Val-Arg-Pro (VRP), Leu-Lys-Tyr (LKY), Val-Arg-Tyr (VRY), and Val-Val-His-Pro-Lys-Glu-Ser-Phe [VVHPKESF (V-F)] on tumor necrosis factor alpha (TNFα)-induced endothelial inflammation and oxidative stress in human vascular endothelial EA.hy926 cells. " 08/01/1981 - "The amino acid sequence of 25 nmol of the peptide was Asp-Arg-Val-Try-Ile-His-Pro-Phe, the same covalent structure as that of angiotensin II. Therefore, under physiologic conditions, in the absence of renin or angiotensin converting enzyme, a human neutrophil neutral protease cleaves a plasma protein to yield angiotensin II. This pathway provides a mechanism through which the neutrophil may alter local blood flow during inflammation by generation of a potent vasoactive peptide."
2.	Essential Hypertension 05/20/1984 - "In this study, the effects of angiotensin II (A II, Asn-Arg-Val-Tyr-Val-His-Pro-Phe) and angiotensin III (A III, Arg-Val-Tyr-Ile-His-Pro-Phe) on blood pressure (B.P.), pulse rate, several hormones [plasma renin activity (PRA), plasma aldosterone (PA), ACTH, plasma cortisol (PC), urinary catecholamines and urinary aldosterone] and urinary electrolytes were investigated in 9 male patients with essential hypertension [mean age 36.2 +/- 4.1 (S.E.) years]. "
3.	Neoplasms (Cancer) 11/01/2009 - "Interestingly, the His/Pro-rich peptide bound to the vessel wall in tissue from cancer patients but not to the vasculature in tissue from healthy persons. " 11/01/1998 - "Four distinct sequence alterations were identified: (a) in one gastric and one esophageal tumor, an A to C transversion occurred at nucleotide 5795 (CAC-->CCC), leading to a His-->Pro substitution at codon 179; (b) a second esophageal tumor had a C to T transition at nucleotide 8291 (ACC-->ATC), leading to a Thr-->Ile substitution at codon 277 of IGFBP-3; (c) one alteration comprised a G to C transversion in exon 1 at nucleotide 2132 (GGG-->GCG), leading to a Gly-->Ala substitution at codon 32 in two gastric cancers, seven esophageal cancers, and nine colon cancers; and (d) a C to G transversion located 17 nucleotides from the 3' splice site in intron 1 was observed in three colon cancers and four esophageal cancers. "
4.	Non-alcoholic Fatty Liver Disease 09/01/2023 - "The naturally occurring compound cyclo histidine-proline (His-Pro) (CHP) is an interesting candidate for NAFLD management, given its safety profile and anti-inflammatory effects. "
5.	Proteostasis Deficiencies 01/01/2018 - "In this context we discuss the possible utility of clyclo (His-Pro) as a promising future therapeutic option for protein misfolding disorders."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	leucyl-lysyl-tyrosine
4.	lysylglutamic acid
5.	arginylproline
6.	valylvaline (Val-Val)
7.	Renin
8.	Angiotensin II
9.	arginylvaline
10.	Hydrocortisone (Cortisol)