|1.||Santin, Alessandro D: 8 articles (12/2015 - 05/2005)|
|2.||McClane, Bruce A: 7 articles (01/2013 - 01/2008)|
|3.||Bellone, Stefania: 6 articles (12/2015 - 05/2005)|
|4.||Pecorelli, Sergio: 6 articles (12/2015 - 05/2005)|
|5.||Kojima, Takashi: 5 articles (09/2012 - 09/2011)|
|6.||Sawada, Norimasa: 5 articles (09/2012 - 09/2011)|
|7.||Cocco, Emiliano: 4 articles (12/2015 - 01/2010)|
|8.||Smedley, James G: 4 articles (10/2011 - 09/2007)|
|9.||Schwartz, Peter E: 3 articles (12/2015 - 01/2010)|
|10.||Rutherford, Thomas J: 3 articles (12/2015 - 01/2010)|
|1.||Neoplasm Metastasis (Metastasis)
09/01/2007 - "Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis."
08/01/2012 - "Although the functional implications are only starting to unravel, claudin-4 seems to play an important role in tumour cell invasion and metastasis, and its dual role as receptor of Clostridium perfringens enterotoxin (CPE) opens exciting avenues for molecular targeted approaches. "
08/05/2008 - "As a result of its prominent expression in both primary and secondary PCas, together with its established role as a receptor for Clostridium perfringens enterotoxin, claudin-4 may be useful as a potential marker and therapeutic target for PCa metastases."
|2.||Ovarian Neoplasms (Ovarian Cancer)
12/15/2011 - "Because this tight junction protein is the natural high-affinity receptor for Clostridium perfringens enterotoxin (CPE), we have extensively investigated the sensitivity of ovarian cancer stem cells to CPE treatment in vitro and in vivo. "
12/15/2011 - "Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of Clostridium perfringens enterotoxin."
08/01/2012 - "Clostridium perfringens enterotoxin may be a novel tumor-targeted therapy for ovarian cancers. "
01/01/2010 - "Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer."
01/01/2013 - "Claudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapy."
12/05/2014 - "Prevalence of Clostridium perfringens, Clostridium perfringens enterotoxin and dysbiosis in fecal samples of dogs with diarrhea."
08/01/2012 - "Only Clostridium perfringens enterotoxin A gene was significantly more common in dogs with diarrhea (64%) than in dogs with normal feces (40%). "
08/01/2012 - "Other enteropathogens identified in cats with and without diarrhea included Clostridium perfringens enterotoxin A (42% and 50%, respectively), Cryptosporidium spp (10% and 20%, respectively), Giardia spp (20% and 8%, respectively), Cystoisospora spp (14% and 10%, respectively), hookworms (10% and 18%, respectively), ascarids (6% and 16%, respectively), Salmonella spp (6% and 4%, respectively), astrovirus (8% and 2%, respectively), feline panleukopenia virus (4% and 4%, respectively), calicivirus (0% and 2%, respectively), and Spirometra spp (0% and 2%, respectively). "
06/01/2008 - "We examined the incidence of nosocomial diarrhea caused by Clostridium perfringens enterotoxin (CPEnt) in three tertiary hospitals in the Tsukuba-Tsuchiura district, Japan. "
04/01/2008 - "Clostridium perfringens enterotoxin in antibiotic-associated diarrhea."
04/01/2015 - "Clostridium perfringens enterotoxin (CPE) and CPE-binding domain (c-CPE) for the detection and treatment of gynecologic cancers."
01/01/2015 - "In this context, the claudin-targeted bacterial Clostridium perfringens enterotoxin (CPE) is an attractive new type of suicide oncoleaking gene, which as pore-forming protein exerts specific and rapid toxicity towards claudin-3- and -4-overexpressing cancers. "
02/14/2014 - "We previously found that claudin (CL) is a potent target for cancer therapy using a CL-3 and -4-targeting molecule, namely the C-terminal fragment of Clostridium perfringens enterotoxin (C-CPE). "
01/01/2013 - "However, these results also suggest caution during therapeutic use of CPE, which might trigger toxic side effects in normal human tissues producing hCldn-8 or -14, as well as in those producing hCldn-3 or -4. Clostridium perfringens enterotoxin (CPE) is responsible for the gastrointestinal symptoms of the second-most-common bacterial food-borne illness and is also being explored for use as a cancer therapeutic or for increasing drug delivery. "
05/01/2012 - "Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors."
|5.||Sudden Infant Death (SID)
04/01/1987 - "This study identifies the presence of Clostridium perfringens type A enterotoxin (CPE) in some gastrointestinal and serum samples from babies who had died of the Sudden Infant Death Syndrome (SIDS) and other causes. "
04/01/1987 - "A hypothesis concerning Clostridium perfringens type A enterotoxin (CPE) and sudden infant death syndrome (SIDS)."
|1.||Proteins (Proteins, Gene)
|5.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|8.||Clostridium difficile tcdA protein
|10.||Complementary DNA (cDNA)
|1.||Drug Therapy (Chemotherapy)
|2.||Heterologous Transplantation (Xenotransplantation)