endodeoxyribonuclease VII

cleaves Holliday structures in vitro by cutting 2 strands of the same polarity at or near the branch point

Also Known As:

T4 endonuclease VII; T4E7 resolvase; endonuclease VII

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Infections 04/29/2003 - "The accumulation of blocked forks increased in endonuclease VII-deficient infections, suggesting that endonuclease cleavage contributes to fork processing in vivo. " 08/01/1996 - "Fourth, the coupled repair/replication reaction is only partly dependent on endonuclease VII (gp49), suggesting that either another Holliday-junction-cleaving activity or an alternate resolution pathway is active during T4 infections. "
2.	Marfan Syndrome (Marfan's Syndrome) 07/01/2000 - "Enzymatic mutation detection (EMD) of novel mutations (R565X and R1523X) in the FBN1 gene of patients with Marfan syndrome using T4 endonuclease VII."

1.	Cruciform DNA (Holliday Junctions)
2.	Endonucleases