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haptoglobin-hemoglobin complex

this is a normal physiological complex

Also Known As:

hemoglobin-haptoglobin complex

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Zaitseva, N V: 1 article (01/2016)
2.	Zemlyanova, M A: 1 article (01/2016)
3.	Beschorner, R: 1 article (01/2011)
4.	Haybaeck, J: 1 article (01/2011)
5.	Holfelder, K: 1 article (01/2011)
6.	Meyermann, R: 1 article (01/2011)
7.	Schittenhelm, J: 1 article (01/2011)
8.	Trautmann, K: 1 article (01/2011)
9.	Azarov, Ivan: 1 article (06/2008)
10.	Basu, Swati: 1 article (06/2008)

Related Diseases

1.	Hemolysis 05/01/1992 - "Measurement of serum haptoglobin by immunoturbidimetry was markedly interfered with hemolysis because of haptoglobin-hemoglobin complex formation. " 01/01/2011 - "The main function of CD163 (hemoglobin scavenger receptor) is to bind the hemoglobin-haptoglobin complex, thereby mediating extravasal hemolysis. " 01/01/2016 - "Increased serum level of vanadium disorders transport of apoproteins incorporated into lipoproteins; increased serum level of nickel activates hemolysis of RBC, disorders speed of hemoglobin-haptoglobin complex formation and its subsequent utilization by hepatocytes. "
2.	Adenomatous Polyps 12/01/1999 - "The sensitivity for detecting large adenomatous polyps was 54% with hemoglobin, 76% with the hemoglobin-haptoglobin complex at a cutoff point of 1.5 microg/g feces, 73% with the hemoglobin-haptoglobin complex at 2.0 and 2.5 microg/g feces, and 65% with the hemoglobin-haptoglobin complex at 3.0 microg/g feces. " 12/01/1999 - "Immunological determination of the hemoglobin-haptoglobin complex in feces has a comparable sensitivity as the fecal hemoglobin assay for colorectal carcinomas and a significantly higher sensitivity for adenomatous polyps but a significantly lower specificity. "
3.	Colorectal Neoplasms (Colorectal Cancer) 12/01/1999 - "Detection of colorectal neoplasms by the highly sensitive hemoglobin-haptoglobin complex in feces." 12/01/1999 - "Immunological determination of the hemoglobin-haptoglobin complex in feces has a comparable sensitivity as the fecal hemoglobin assay for colorectal carcinomas and a significantly higher sensitivity for adenomatous polyps but a significantly lower specificity. "
4.	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 06/01/2008 - "We provide computer simulations showing that a twofold difference in the rate of uptake of the haptoglobin-hemoglobin complex by macrophages significantly affects nitric oxide bioavailability thereby providing a plausible explanation for why there is more vasospasm after subarachnoid hemorrhage in individuals and transgenic mice homozygous for the Hp 2 allele."
5.	Hepatocellular Carcinoma (Hepatoma) 08/12/1992 - "The uptake of radio-labeled hemoglobin-haptoglobin complex (Hb-Hp) by human hepatoma PLC/PRF/5 and HepG2 cells was investigated in an attempt to characterize the uptake process and intracellular transport. "

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)
2.	Scavenger Receptors (Scavenger Receptor)
3.	Vanadium
4.	Nitric Oxide (Nitrogen Monoxide)
5.	Nickel
6.	Lipoproteins (Lipoprotein)
7.	Haptoglobins
8.	Apoproteins