macrophage aggregation factor

heat stable protein inactivated by alpha-chymotrypsin & partially inactivated by trypsin; not affected by neuraminidase; will aggregate peritoneal exudate cells & its production was correlated with delayed cutaneous hypersensitivity

Also Known As:

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Osteoarthritis 09/01/1984 - "Performing histo-morphologic studies of knee joints in several hundred mice of the strains C57 black, STR/1N and MAGf, showing a disposition for spontaneous osteo-arthrosis, we found tentative reparative processes in many cases. "
2.	Delayed Hypersensitivity (Hypersensitivity, Type IV) 09/01/1977 - "This factor was designated macrophage-agglutinating factor (MAgF) because it is similar to the previously described factor found in lung lavages of rabbits exhibiting a BCG-induced pulmonary delayed hypersensitivity reaction. " 03/01/1973 - "Delayed hypersensitivity to cartilage constituents was studied by peripheral lymphocyte transformation employing [(3)H]thymidine incorporation and the release of macrophage aggregation factor. "
3.	Granuloma 01/01/1987 - "The production of macrophage aggregation factor (MAF) by in vitro cultured Schistosoma mansoni egg granulomas isolated from experimentally infected mice." 09/01/1977 - "The role of MAgF in vivo is unknown, but it is postulated that it may cause the adherence of macrophages during granuloma formation."
4.	Genu Varum 01/01/1986 - "The C57 Black strain exhibits a certain tendency to develop genu valgum, and the STR/IN strain almost regularly shows genu varum; no distinct tendency is detectable in MAGf mice. "
5.	Genu Valgum 01/01/1986 - "The C57 Black strain exhibits a certain tendency to develop genu valgum, and the STR/IN strain almost regularly shows genu varum; no distinct tendency is detectable in MAGf mice. "

Related Drugs and Biologics

1.	Thymidine

Related Therapies and Procedures

1.	Hysterectomy