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chlorendic acid

RN given refers to cpd without isomeric designation

Also Known As:

chlorendic acid, (endo,endo)-isomer

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Bridged-Ring Compounds: 1
      - Bridged Bicyclo Compounds
        Norbornanes: 4
        chlorendic acid: 3
Polycyclic Compounds: 6
- Bridged-Ring Compounds: 1
  - Bridged Bicyclo Compounds
    - Norbornanes: 4
      - chlorendic acid: 3

Related Diseases

1.	Carcinogenesis 04/01/1987 - "Toxicology and carcinogenesis studies of chlorendic acid (greater than 98% pure) were conducted by administering the chemical in feed to groups of 50 male and 50 female F344/N rats and B6C3F1 mice at concentrations of 0, 620, or 1,250 ppm for 103 weeks. " 04/01/1987 - "NTP Toxicology and Carcinogenesis Studies of Chlorendic Acid (CAS No. 115-28-6) in F344/N Rats and B6C3F1 Mice (Feed Studies)."
2.	Inflammation (Inflammations) 04/01/1987 - "In the 2-year chlorendic acid feed studies, incidences of nonneoplastic lesions of the liver in dosed male rats (cystic degeneration) and dosed female rats (granulomatous inflammation, pigmentation, and bile duct hyperplasia) were increased. "
3.	Hyperplasia 04/01/1987 - "In the 2-year chlorendic acid feed studies, incidences of nonneoplastic lesions of the liver in dosed male rats (cystic degeneration) and dosed female rats (granulomatous inflammation, pigmentation, and bile duct hyperplasia) were increased. "
4.	Adenoma (Adenomas) 04/01/1987 - "Under the conditions of these 2-year feed studies, there was clear evidence of carcinogenicity of chlorendic acid for male F344/N rats as shown by increased incidences of neoplastic nodules of the liver and acinar cell adenomas of the pancreas. " 04/01/1987 - "Increased incidences of alveolar/bronchiolar adenomas and preputial gland carcinomas may also have been related to the administration of chlorendic acid. "
5.	Body Weight (Weight, Body) 04/01/1987 - "The estimated mean daily consumption of chlorendic acid was 27 and 56 mg/kg body weight for low dose and high dose male rats and 39 and 66 mg/kg for low dose and high dose female rats. " 05/01/1982 - "[14C]Chlorendic acid was absorbed after an oral dose of 7.7 mumol per kilogram of body weight. "

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