|1.||Bielawski, Krzysztof: 2 articles (01/2009 - 05/2008)|
|2.||Popławska, Bozena: 2 articles (01/2009 - 05/2008)|
|3.||Bielawska, Anna: 2 articles (01/2009 - 05/2008)|
|4.||Najajreh, Yousef: 2 articles (07/2006 - 11/2002)|
|5.||Gibson, Dan: 2 articles (07/2006 - 11/2002)|
|6.||Perez, Jose Manuel: 2 articles (07/2006 - 11/2002)|
|7.||Monika, Cyuńczyk: 1 article (01/2014)|
|8.||Elżbieta, Skrzydlewska: 1 article (01/2014)|
|9.||Krzysztof, Bielawski: 1 article (01/2014)|
|10.||Anna, Bielawska: 1 article (01/2014)|
08/01/1979 - "The mechanism of action of cis-dichloro-bis (isopropylamine) trans dihydroxyplatinum IV (CHIP) on Chinese hamster and C3H mouse tumor cells and its interaction with X-irradiation."
09/01/1983 - "cis-Dichloro-trans-dihydroxy-bis-isopropylamine platinum(IV) (CHIP), a second-generation platinum complex with little or no nephrotoxicity in preclinical studies, has undergone phase I clinical testing and initial pharmacokinetic evaluation in 26 patients with solid tumors who received 40 courses of treatment. "
01/01/1983 - "Pharmacokinetics of cis-dichloro-trans-dihydroxy-bis-isopropylamine platinum IV (CHIP) in patients with advanced cancer."
01/01/2001 - "Cellular Uptake, DNA Binding and Apoptosis Induction of Cytotoxic Trans-[PtCl(2)(N,N-dimethylamine)(Isopropylamine)] in A2780cisR Ovarian Tumor Cells."
08/15/2008 - "The N-methylamine and N-isopropylamine derivatives were also evaluated as antitumor agents in athymic nude mice with MDA-MB-435 human tumor xenografts. "
|3.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
|4.||Breast Neoplasms (Breast Cancer)
05/01/2008 - "A series of platinium(II) complexes of formula [Pt2L4(berenil)2]Cl4.4HCl.2H2O where L is piperidine (1), 4-picoline (2), 3-picoline (3) or isopropylamine (4) was prepared and their cytotoxicity have been tested against the growth of human breast cancer cells. "
06/01/1988 - "Clinical trial of iproplatin (cis-dichloro-trans-dihydroxy-bis-isopropylamine platinum IV, CHIP) in patients with advanced breast cancer."
01/01/2014 - "Pt2(isopropylamine)4berenil2 and Pt2(piperidine)4(berenil)2 notably affected the cellular metabolism of estrogen-positive breast cancer cells. "
01/01/2009 - "Four novel dinuclear platinum(II) complexes of formula [Pt2L4(berenil)2]Cl4 (Pt1-Pt4) where L is piperazine (Pt1), 4-picoline (Pt2), 3-picoline (Pt3) or isopropylamine (Pt4) were compared to cisplatin in respect to collagen biosynthesis, beta1- integrin receptor, IGF-I receptor, phosphorylated MAP-kinases (ERK1/ERK2 and p38), phosphorylated Akt kinase expression and appearance of apoptosis in MCF-7 breast cancer cells. "
|5.||Chromosome Aberrations (Chromosome Abnormalities)
04/01/1983 - "The mode of action of cis dichloro-bis (isopropylamine) trans dihydroxy platinum IV (CHIP) studied by the analysis of chromosome aberration production."
06/01/1993 - "The anaphase-telophase Allium test showed no effect for the glyphosate isopropylamine salt, but a significant increase in chromosome aberrations appeared after treatment with Roundup at concentrations of 1.44 and 2.88 mg/l when calculated as glyphosate isopropylamine. "
|8.||dimethylamine (dimethylamine nitrate)
|1.||Heterologous Transplantation (Xenotransplantation)